Recombinant Human RASSF6 Protein, N-His

Description of Recombinant Human RASSF6 Protein, N-His

Recombinant Human RASSF6 Protein, also known as Ras association domain-containing protein 6, is a protein that plays an important role in regulating cell growth and apoptosis. This protein is encoded by the RASSF6 gene and is part of the RASSF family of proteins. Recombinant Human RASSF6 Protein is produced through recombinant DNA technology and has a variety of applications in scientific research and medical treatments.

Recombinant Human RASSF6 Protein is a 307 amino acid protein with a molecular weight of approximately 35 kDa. It contains a Ras association (RA) domain, a SARAH (Sav/Rassf/Hpo) domain, and a C-terminal coiled-coil domain. The RA domain is responsible for binding to small GTPases, while the SARAH domain is involved in protein-protein interactions. The C-terminal coiled-coil domain is important for the formation of dimers and oligomers. These structural features make Recombinant Human RASSF6 Protein a key player in signaling pathways that regulate cell growth and apoptosis.

Recombinant Human RASSF6 Protein has been shown to interact with various proteins involved in cell signaling, including the Ras family of small GTPases, MST kinases, and the tumor suppressor protein, p53. Through these interactions, Recombinant Human RASSF6 Protein can regulate cell growth and induce apoptosis. Studies have also shown that this protein is involved in the regulation of the Hippo signaling pathway, which controls organ size and tissue regeneration. Additionally, Recombinant Human RASSF6 Protein has been found to play a role in DNA damage response and cell cycle progression.

Recombinant Human RASSF6 Protein has a wide range of applications in both scientific research and medical treatments. In research, this protein is often used as a tool to study cell signaling pathways and their role in various diseases. It can be used in biochemical assays to investigate protein-protein interactions and to screen for potential drug targets. Recombinant Human RASSF6 Protein can also be used in cell culture experiments to study its effects on cell growth and apoptosis.

In terms of medical applications, Recombinant Human RASSF6 Protein has shown potential as a therapeutic target for cancer treatment. Studies have found that this protein is downregulated in various types of cancer, and its overexpression can induce apoptosis in cancer cells. Additionally, Recombinant Human RASSF6 Protein has been found to enhance the sensitivity of cancer cells to chemotherapy drugs. This makes it a promising candidate for the development of new cancer treatments.

Furthermore, Recombinant Human RASSF6 Protein has also been investigated for its potential role in neurological disorders such as Alzheimer’s disease. Studies have shown that this protein is involved in the regulation of neuronal cell death and may play a role in the progression of Alzheimer’s disease. By understanding its function, Recombinant Human RASSF6 Protein could potentially be targeted for therapeutic interventions in this disease.

In summary, Recombinant Human RASSF6 Protein is a key player in regulating cell growth and apoptosis through its interactions with various signaling proteins. Its structural features and diverse functions make it a valuable tool for scientific research and a potential therapeutic target for diseases such as cancer and Alzheimer’s. Further studies on this protein will continue to provide insights into its role in cellular processes and its potential for medical applications.

Keywords: Recombinant protein, antigen, RASSF6, cell growth, apoptosis, signaling pathways, cancer, Alzheimer’s disease.