Antibody production
-
Antibody productionHow to leverage recombinant monoclonal antibody production to increase clinical success rates
Philippe Funfrock
Ever since the onset of recombinant technology, therapeutic biologics production has gradually shifted from native to recombinant expression. Today, recombinant monoclonal antibody production is the preferred method to obtain these…
-
Fundamental and advanced methods to improve monoclonal antibody production in vitro
Ever since the discovery of the hybridoma technology and its inherent limitations, monoclonal antibody production has gradually shifted from hybridoma-based… Read More
-
Will a single COVID-19 drug be enough to treat all patients?
As more and more biotherapeutics enter the early stages of clinical development, scientists are questioning if current approaches will be… Read More
-
How will monoclonal antibody production by hybridoma technology evolve in the coming decades
For the past decades, the hybridoma technology has allowed us to leverage potent and highly specific antibodies for therapy, research,… Read More
-
Will camelid antibodies offer a solution to solve the COVID-19 pandemic?
The emergence of the zoonotic pathogen, SARS-CoV-2, resulted in a global pandemic and caused the deaths of hundreds of thousands… Read More
-
Can mRNA therapeutics overcome the limitations of typical monoclonal antibody production processes?
Antibodies have driven the development of research and medicine. Their specificity, stability, and reduced immunogenicity have made them one of… Read More
-
What are chimeric antibodies?
Considered by many researchers as intermediate molecules, chimeric antibody constructs have been gradually losing ground to more effective molecules such… Read More
-
How are mouse monoclonal antibodies humanized: current approaches and limitations
Mouse monoclonal antibodies were the first to ever be produced in vitro. However, early-stage clinical evaluation of these molecules led… Read More
-
Fully human antibodies that will make the news in 2020
As the demand for fully human antibodies continues to rise, so does the proportion of clinical approvals of this type… Read More
-
Why humanized antibody production may thrive in the 2020s
For the first time, humanized and fully human antibodies are almost on equal terms. Up to 2019, 38 humanized antibodies… Read More
