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Antibody productionFundamental and advanced methods to improve monoclonal antibody production in vitro
Philippe Funfrock
Ever since the discovery of hybridoma technology and its inherent limitations, monoclonal antibody production has gradually shifted from in vivo methods towards recombinant in vitro systems. Today, stable CHO cell…
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A guide to mammalian cell-based expression systems
What is a mammalian protein expression system and which mammalian cell lines and vectors are best for recombinant protein production?… Read More
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Applications of the XtenCHO™ Race transient expression system
XtenCHO™ Race combines the high productivity of a new CHO-derived cell line with the best reagents for the rapid production… Read More
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What are the advantages of using a transient CHO system over HEK293?
Chinese Hamster Ovary (CHO) and Human Embryonic Kidney (HEK) systems are the major cell lines used in transient and high-yield… Read More
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No-tag purification
No-tag purification… Read More
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Putting rAbs on the map – recombinant antibodies as invaluable research tools
Antibodies are vital reagents for biological and biochemical research, useful for determining protein function under normal and pathophysiological conditions. Due… Read More
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Hands-on tips on how to improve transient expression
Mammalian cell lines are the preferred expression system for biopharmaceutical production and are widely used in recombinant protein expression for… Read More
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A guide to recombinant protein expression: hosts, vectors & tags
Recombinant protein expression is considered one of the most important breakthroughs ever achieved in the life sciences. Decades of research… Read More
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How to leverage recombinant monoclonal antibody production to increase clinical success rates
Ever since the onset of recombinant technology, therapeutic biologics production has gradually shifted from native to recombinant expression. Today, recombinant… Read More
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What essential steps are necessary to accelerate recombinant antibody expression?
Transformation or transfection are still considered one of the most challenging steps in custom recombinant antibody production. The choice… Read More