Store at - 20℃ to -80℃.
It is recommended that the protein be aliquoted for optimal storage.
Brand
ProteoGenix
Host species
Mammalian cells
Fragment Type
Met1-Asp239
Aliases /Synonyms
IL2RB
Reference
PX-P4103
Note
For research use only
Description of CD122 Recombinant Protein
General information on CD122 Recombinant Protein:
The interleukin-2 receptor (IL-2R), also known as the β subunit receptor of the β subunit IL-2, subunit of the IL-2 β and IL-2RB receptor, participates in the immune response of T cells. ability to bind interleukin 2, CD122 / IL-2RB exists in three forms. The low affinity form is a monomer of the alpha subunit and does not participate in signal transmission. The intermediate affine form is composed of α / β subunit heterodimers, while the high affinity form is composed of α / β / gamma heterotrimers. Both forms of medium and high affinity for CD122 / IL-2RB are involved in receptor-mediated endocytosis and interleukin-2-mediated mitotic signal transduction. CD122 / IL-2RB expression is limited to older B22 + cells (CD43 + CD24- prepro B cells, fraction A), which can proliferate to IL-2 strongly without any stromal cells, but not to IL-15 A High affinity form of the receptor is expressed in activated T lymphocytes, activated B lymphocytes and activated macrophages. CD122 / IL-2RB plays a role in regulating normal lymphocyte development.
Reviews
There are no reviews yet.