Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade

Reference:
Product nameGimistotug Biosimilar - Anti-ACT35 antigen mAb - Research Grade
SourceCAS: 2768487-95-0
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134
ReferencePX-TA2193-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Gimistotug Biosimilar - Anti-ACT35 antigen mAb - Research Grade

Introduction

Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade is a therapeutic antibody that has been developed as a biosimilar to a well-known and widely used monoclonal antibody, ACT35. This biosimilar offers a more cost-effective and accessible option for researchers and clinicians looking to target the ACT35 antigen for therapeutic purposes. In this article, we will explore the structure, activity, and potential applications of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade.

Structure of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade

Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade is a monoclonal antibody, meaning it is produced by a single clone of cells. It is a type of immunoglobulin G (IgG) antibody, with a molecular weight of approximately 150 kDa. The antibody is composed of two heavy chains and two light chains, each with a constant and variable region. The variable region is responsible for binding to the ACT35 antigen, while the constant region is responsible for immune effector functions.

Activity of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade

The primary activity of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade is the specific binding to the ACT35 antigen. This binding is mediated by the variable region of the antibody, which recognizes and binds to a specific epitope on the antigen. This binding can result in various downstream effects, such as blocking the interaction between ACT35 and its receptor, or triggering immune effector functions such as antibody-dependent cellular cytotoxicity (ADCC) or complement-dependent cytotoxicity (CDC).

In addition to its binding activity, Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade also has a long half-life in the body, allowing for sustained therapeutic effects. It also has a low immunogenicity profile, meaning it is less likely to elicit an immune response in patients.

Therapeutic Target: ACT35 Antigen

The therapeutic target of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade is the ACT35 antigen. This antigen is a cell surface receptor that is overexpressed in various types of cancer, including breast, lung, and colon cancer. It is also involved in the development of autoimmune diseases, making it a promising target for therapeutic intervention.

ACT35 is known to play a role in cell growth, survival, and proliferation, making it an attractive target for cancer therapy. By targeting and blocking the activity of this antigen, Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade can potentially inhibit tumor growth and promote cell death.

Potential Applications of Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade

Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade has potential applications in both cancer therapy and autoimmune disease treatment. In cancer therapy, it can be used as a monotherapy or in combination with other treatments, such as chemotherapy or targeted therapy. By targeting the ACT35 antigen, Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade can potentially enhance the efficacy of these treatments and reduce the risk of tumor recurrence.

In autoimmune disease treatment, Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade can be used to block the activity of ACT35 and prevent the development of autoimmune responses. This can help alleviate symptoms and improve the quality of life for patients with these conditions.

Conclusion

Gimistotug Biosimilar – Anti-ACT35 antigen mAb – Research Grade is a promising therapeutic antibody that offers a more accessible and cost-effective option for targeting the ACT35 antigen. Its specific binding activity, long half-life, and low immunogenicity make it a valuable tool for researchers and clinicians in the fields

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