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📢 -40% on Recombinant Antibody Production. Available until November 16th on your first order. Code: RECAB40

IP-Free Humanized Mouse Models for Monoclonal Antibody Discovery

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Get the high-affinity antibodies you need to advance your therapeutic project with confidence

  • Receive 10 high-affinity antibodies
  • Test where it matters most, in your samples
  • Advance with 3 guaranteed winners
  • Own every sequence. With full IP freedom

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3 Guaranteed Lead Antibodies. Validated in Your Own Lab.
Fully Human. Fully Yours.

Because discovery doesn’t mean uncertainty

Receive 10 High-Affinity Antibodies

  • Up to 10 fully human antibodies, purified and ELISA-validated for antigen binding, with full sequence information included.

Test Where It Matters Most, In Your Samples

  • Test directly in your lab to identify the three top-performing antibodies under your experimental conditions. 

Advance with 3 Guaranteed Winners

  • We guarantee three high-affinity, sequenced, and purified antibodies.
  • If the first panel does not fulfill the required performance, we supply additional sequences until three candidates are secured.

Own Every Sequence. With Full IP Freedom

  • With no royalties or licensing fees, you maintain complete control over downstream development.

Obtain Fully Human Antibodies with Unmatched Affinity and Diversity

Harness the power of humanized mouse models combined with single B-cell screening to obtain fully human antibodies with exceptional affinity, diversity, and functionality.

Skip Affinity Maturation

Natural in vivo maturation ensures that antibodies possess therapeutic-grade affinity and specificity from the start, thereby reducing the need for optimization steps downstream.

Unlock Diversity Across Sequence, Structure & Function

Broad antibody sequence and structural repertoires through a natural immune response, reducing the risk of limited candidates or repeated sequences common in in vitro display systems.

Break Through the Challenging Targets

From GPCRs to ion channels, humanized mice generate antibodies against your most challenging targets that are difficult to target with synthetic libraries or recombinant approaches.

De-risk Your Therapeutic Pipeline

Naturally affinity-matured antibodies ensure optimal developability properties, smoothing development and regulatory paths.

 

Roadmap to Your First 10 Human Antibodies (8 to 11 weeks)

10 Ready-to-Test Purified Antibodies (8 to 11 weeks)
Time 4-6 weeks 2-3 weeks 2 weeks
Steps Immunization in Proprietary Humanized Mice Single B-Cell Screening & Validation Recombinant Production of Up to 10 Antibodies
Description Antigen validation by SDS-Page and immunization with our RocketAbs protocol. PBMCs and spleen lymphocyte isolation, single B-cell sorting by FACS, B-cell cultivation, screening.
Obtention of up to 30 supernatant samples.
Top clones are sequenced, and transient expression is performed.
Receive 10 antibodies, purified and ELISA-validated for antigen binding, ready for direct testing in your own assays.

Keep Your Focus on Discovery, Not on IP Fees

We ensure zero royalties, zero licensing fees at every stage, from discovery to market.

 

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IP-Free Policy with ProteoGenix

FAQs

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