Epidermal Growth Factor (EGF) and Epidermal Growth Factor Receptor (EGFR)
Proteins
Epidermal Growth Factor (EGF) and Epidermal Growth Factor Receptor (EGFR) are two proteins that are involved in the regulation of cell growth and division. EGF is a small protein that binds to the EGFR on the surface of cells. This binding initiates a signal transduction cascade which results in the activation of many intracellular pathways that control cell proliferation and differentiation.
Antibodies
Antibodies against EGF and EGFR can be used to detect the presence of these proteins in a sample. Monoclonal antibodies are produced that specifically bind to either EGF or EGFR to detect their presence. These antibodies can be used in a variety of assays, such as western blotting and immunohistochemistry, to detect the presence of these proteins in a sample.
Drug Target
EGFR has been identified as an important drug target for the treatment of cancer. Drugs that target EGFR can inhibit the binding of EGF to EGFR, thus preventing the activation of the signal transduction cascade and the subsequent cell proliferation and differentiation. These drugs can be used to inhibit the growth of cancer cells and can be used in combination with other treatments to improve the effectiveness of cancer treatments.
ProteoGenix
ProteoGenix is a biotechnology company that specializes in the production of recombinant proteins, including EGF and EGFR. We have developed a platform for the production of recombinant proteins that can be used for research applications in therapeutic field.
