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| Size | 100ug, 1MG |
|---|---|
| Brand | ProteoGenix |
| Product type | Recombinant Proteins |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Batiraxcept Biosimilar - Anti-AXLLG fusion protein - Research Grade |
|---|---|
| Expression system | XtenCHO |
| Purity | >90% by SDS-PAGE. |
| Buffer | 0.01M PBS, pH 7.4. |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | 4°C for short term; -20°C for long term |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6 |
| Reference | PX-TA2004 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | Fusion - [AXL (AXL receptor tyrosine kinase, ARK, JTK11, Tyro7, UFO)]2 - IGHG1 Fc (Fragment constant) |
Batiraxcept Biosimilar is a novel anti-AXLLG fusion protein that has gained attention in the field of biotechnology as a potential therapeutic agent. This biosimilar is a recombinant protein that has been designed to target and inhibit the activity of the AXLLG protein, which is known to play a critical role in various pathological conditions. In this article, we will provide a scientific description of Batiraxcept Biosimilar, including its structure, activity, and potential applications.
Batiraxcept Biosimilar is a fusion protein composed of two distinct domains – the antibody domain and the therapeutic domain. The antibody domain is derived from a monoclonal antibody, which specifically binds to the AXLLG protein, while the therapeutic domain is derived from a protein that inhibits the activity of the AXLLG protein. These two domains are connected by a linker sequence, which provides the necessary flexibility for the protein to bind to its target.
The antibody domain of Batiraxcept Biosimilar is a Y-shaped molecule, consisting of two heavy chains and two light chains. Each chain is composed of a variable region and a constant region. The variable region is responsible for binding to the AXLLG protein, while the constant region provides stability to the molecule. The therapeutic domain, on the other hand, is a small protein that is known to inhibit the activity of the AXLLG protein through a specific mechanism.
The primary activity of Batiraxcept Biosimilar is to inhibit the activity of the AXLLG protein. The AXLLG protein is known to play a critical role in various pathological conditions, including cancer, inflammation, and autoimmune diseases. It is a key mediator of cell signaling pathways that regulate cell growth, survival, and migration. In pathological conditions, the AXLLG protein is overexpressed, leading to abnormal cell growth and proliferation. By specifically targeting and inhibiting the activity of the AXLLG protein, Batiraxcept Biosimilar has the potential to treat a wide range of diseases.
The mechanism of action of Batiraxcept Biosimilar involves two steps – binding to the AXLLG protein and inhibiting its activity. The antibody domain of Batiraxcept Biosimilar binds to the AXLLG protein with high specificity and affinity, preventing it from interacting with its cellular receptors. This binding also triggers a conformational change in the AXLLG protein, exposing its active site. The therapeutic domain of Batiraxcept Biosimilar then binds to this active site, inhibiting the activity of the AXLLG protein. This dual mechanism of action makes Batiraxcept Biosimilar a potent inhibitor of the AXLLG protein.
Batiraxcept Biosimilar has a wide range of potential applications in the field of biotechnology and medicine. Its ability to specifically target and inhibit the activity of the AXLLG protein makes it a promising therapeutic agent for various pathological conditions. Some of the potential applications of Batiraxcept Biosimilar include:
1.
Cancer therapy – The overexpression of the AXLLG protein is associated with various types of cancer. By inhibiting the activity of the AXLLG protein, Batiraxcept Biosimilar has the potential to slow down or even stop the growth of cancer cells.
2. Inflammatory diseases – The AXLLG protein is known to play a critical role in the inflammatory response. By inhibiting its activity, Batiraxcept Biosimilar can reduce inflammation and provide relief to patients suffering from inflammatory diseases such as rheumatoid arthritis and psoriasis.
3. Autoimmune diseases – In autoimmune diseases, the immune system mistakenly attacks healthy cells in the body. The AXLLG protein has been implicated in the development of autoimmune diseases. By inhibiting its activity, Batiraxcept Biosimilar can potentially treat these conditions.
In conclusion, Batiraxcept Biosimilar is a novel anti-AXLLG fusion protein with a unique structure and potent activity. Its ability to specifically target and inhibit the activity of the AXLLG protein makes it a promising therapeutic agent for various pathological conditions. With
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