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CD19 Recombinant Protein

Reference: PX-P4077-100
size

100ug

Brand

ProteoGenix

Product type

Recombinant Proteins

Host Species

Mammalian cells

Applications

Elisa, WB

Product nameCD19 Recombinant Protein
Uniprot IDP15391
Uniprot linkhttp://www.uniprot.org/uniprot/P15391
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
SequenceMPPPRLLFFLLFLTPMEVRPEEPLVVKVEEGDNAVLQCLKGTSDGPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPPSEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWAKDRPEIWEGEPPCLPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVHPKGPKSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITARPVLWHWLLRTGGW
Molecular weight45kDa
Protein delivered with Tag?C-terminal His Tag
Purity estimated>90% by SDS-PAGE
BufferPBS pH7.5
Delivery conditionDry Ice
Storage conditionStore at - 20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage.
BrandProteoGenix
Host speciesMammalian cells
Fragment TypeMet1~Trp290
Aliases /Synonyms/
ReferencePX-P4077
NoteFor research use only

Description of CD19 Recombinant Protein

General information on CD19 Recombinant Protein

CD19 Recombinant Protein Structure

CD19 is a transmembrane glycoprotein expressed on the surface of B cells. It is composed of two extracellular immunoglobulin-like domains and a short cytoplasmic tail.

CD19 Recombinant Protein Activity

CD19 plays an important role in the development and function of B cells by mediating signal transduction and cell adhesion. It also interacts with other immune checkpoint proteins to regulate B cell survival, differentiation and activation.

CD19 Recombinant Protein Application

CD19 is an attractive target for antibody-drug conjugates (ADCs) due to its broad expression on B cells. It has been used in clinical trials for the treatment of B cell malignancies such as leukemia and lymphoma.

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