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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG1, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Dargistotug Biosimilar - Anti-VSTM3 mAb - Research Grade |
|---|---|
| Species | Homo sapiens |
| Expression system | XtenCHO |
| Purity | >90% by SDS-PAGE. |
| Buffer | 0.01M PBS, pH 7.4. |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | 4°C for short term; -20°C for long term |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains |
| Reference | PX-TA2050 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
Dargistotug Biosimilar is a novel therapeutic antibody that targets the VSTM3 protein. This biosimilar is designed to mimic the activity of an existing monoclonal antibody (mAb) and has the potential to provide a more affordable and accessible treatment option for patients in need. In this article, we will explore the structure, activity, and potential applications of Dargistotug Biosimilar in more detail.
Dargistotug Biosimilar is a recombinant humanized mAb that is produced using advanced biotechnology techniques. The antibody is composed of two identical heavy chains and two identical light chains, which are connected by disulfide bonds. The variable regions of the antibody are responsible for binding to the target protein, VSTM3, while the constant regions determine the effector functions of the antibody.
The primary activity of Dargistotug Biosimilar is its ability to bind to the VSTM3 protein with high specificity and affinity. VSTM3 is a cell surface protein that is predominantly expressed on immune cells, including T cells, B cells, and natural killer cells. It has been identified as a potential therapeutic target for various diseases, including autoimmune disorders and cancer.
By binding to VSTM3, Dargistotug Biosimilar can modulate the activity of immune cells and potentially regulate immune responses. This can have a beneficial effect in diseases where the immune system is overactive or dysregulated. Additionally, Dargistotug Biosimilar may also have direct cytotoxic effects on VSTM3-expressing cancer cells, making it a promising candidate for cancer therapy.
Dargistotug Biosimilar has the potential to be used in a variety of therapeutic applications. Its primary use is in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By targeting VSTM3, Dargistotug Biosimilar can potentially reduce inflammation and modulate immune responses, providing relief for patients with these conditions.
In addition, Dargistotug Biosimilar may also have applications in cancer therapy. As mentioned earlier, the antibody has the potential to directly kill cancer cells by binding to VSTM3. This makes it a promising candidate for the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors.
Dargistotug Biosimilar is currently in the research grade stage, which means that it is being evaluated in preclinical and early clinical studies. These studies are necessary to determine the safety and efficacy of the antibody in humans before it can be approved for use in patients.
The research grade Dargistotug Biosimilar is also being used to compare its activity and efficacy to the original monoclonal antibody that it is based on. This will ensure that the biosimilar is comparable in terms of structure and function to the original antibody and can provide similar therapeutic benefits.
Dargistotug Biosimilar is a promising therapeutic antibody that targets the VSTM3 protein. Its structure and activity make it a potential treatment option for autoimmune disorders and cancer. As a research grade antibody, it is currently being evaluated in preclinical and early clinical studies to determine its safety and efficacy. If successful, Dargistotug Biosimilar has the potential to provide a more affordable and accessible treatment option for patients in need.
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