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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG1, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Eurestobart Biosimilar - Anti-Ecto-ATP diphosphohydrolase 1 mAb - Research Grade |
|---|---|
| Source | CAS: 2682847-53-4 |
| Species | Human |
| Buffer | 0.01M PBS, pH 7.4 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen |
| Reference | PX-TA1946 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
Eurestobart Biosimilar – Anti-Ecto-ATP diphosphohydrolase 1 mAb – Research Grade is a novel monoclonal antibody that has been developed for targeting a specific enzyme known as Ecto-ATP diphosphohydrolase 1 (E-NTPDase1). This enzyme is involved in the regulation of extracellular ATP levels and plays a crucial role in various physiological and pathological processes. In this article, we will discuss the structure, activity, and potential applications of this biosimilar antibody.
Eurestobart Biosimilar is a monoclonal antibody that is produced by recombinant DNA technology. It is a fully humanized antibody, meaning that it is derived from human cells and has a high affinity for its target. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains are made up of constant and variable regions, while the light chains consist of only variable regions. The variable regions of the antibody are responsible for binding to the target enzyme, E-NTPDase1.
Eurestobart Biosimilar specifically targets E-NTPDase1, which is a cell surface enzyme that hydrolyzes extracellular ATP into ADP. This activity is essential for maintaining the balance of extracellular ATP levels, which is crucial for various cellular processes. However, dysregulation of E-NTPDase1 has been linked to several diseases, including cancer, inflammation, and autoimmune disorders. Eurestobart Biosimilar binds to E-NTPDase1 with high specificity and inhibits its activity, thereby reducing the levels of extracellular ATP. This inhibition can have a therapeutic effect in diseases where E-NTPDase1 is overexpressed or overactive.
Eurestobart Biosimilar has shown promising results in pre-clinical studies and has the potential to be used in various therapeutic applications. Some of the potential applications of this biosimilar antibody are discussed below.
1.
E-NTPDase1 has been found to be overexpressed in several types of cancer, including breast, lung, and colon cancer. Inhibition of this enzyme has been shown to reduce tumor growth and metastasis. Eurestobart Biosimilar, by targeting E-NTPDase1, can potentially be used as a therapeutic agent for the treatment of cancer.
2. Inflammatory Diseases Extracellular ATP has been implicated in the pathogenesis of various inflammatory diseases, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease. By inhibiting E-NTPDase1, Eurestobart Biosimilar can reduce the levels of extracellular ATP and potentially alleviate the symptoms of these diseases.
3.
Autoimmune disorders, such as multiple sclerosis and lupus, are characterized by an overactive immune response against the body’s own tissues. E-NTPDase1 has been shown to play a role in regulating immune responses, and its inhibition by Eurestobart Biosimilar can potentially modulate the immune system and provide therapeutic benefits in these disorders.
4. Diagnostic Tool E-NTPDase1 has been identified as a potential biomarker for various diseases, including cancer and autoimmune disorders. Eurestobart Biosimilar, being a specific inhibitor of this enzyme, can be used as a diagnostic tool for detecting elevated levels of E-NTPDase1 in patients.
Eurestobart Biosimilar – Anti-Ecto-ATP diphosphohydrolase 1 mAb – Research Grade is a novel monoclonal antibody that specifically targets E-NTPDase1. Its structure, activity, and potential applications make it a promising therapeutic agent for various diseases. Further studies and clinical trials are needed to fully evaluate the efficacy and safety of this biosimilar antibody. However, it holds great potential in the field of antibody-based therapies and can potentially improve the treatment options for patients
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