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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG2a, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Fanolesomab Biosimilar - Anti-FUT-4 mAb - Research Grade |
|---|---|
| Expression system | XtenCHO |
| Purity | >90% by SDS-PAGE. |
| Buffer | 0.01M PBS, pH 7.4. |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | 4°C for short term; -20°C for long term |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-Alpha-(1, 3)-fucosyltransferase 4, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase, Fuc-TIV, FCT3A, FUT4, ELFT, FucT-IV |
| Reference | PX-TA1998 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal Antibody |
Fanolesomab Biosimilar is a monoclonal antibody (mAb) that targets the FUT-4 protein. It is a biosimilar version of the original Fanolesomab, which was developed as a diagnostic tool for detecting the presence of FUT-4 in cancer cells. The biosimilar version is designed for research purposes and has the same structure and function as the original Fanolesomab.
The Fanolesomab Biosimilar is a type of immunoglobulin G (IgG) antibody, which is a Y-shaped protein made up of two heavy chains and two light chains. The heavy chains are composed of constant and variable regions, while the light chains only have variable regions. The variable regions are responsible for binding to specific targets, in this case, the FUT-4 protein.
The Fanolesomab Biosimilar is a chimeric antibody, meaning it is made up of both human and mouse components. This allows for better recognition and binding to the FUT-4 protein, as the mouse component provides a higher affinity for the target. The constant regions of the antibody are human, which reduces the risk of an immune response when used in humans.
The main activity of Fanolesomab Biosimilar is to bind to the FUT-4 protein and inhibit its function. FUT-4 is a glycosyltransferase enzyme that is involved in the production of certain carbohydrates on the surface of cells. These carbohydrates play a role in cell adhesion and signaling, and in cancer cells, they can contribute to tumor growth and metastasis.
By binding to FUT-4, Fanolesomab Biosimilar prevents the enzyme from functioning properly, leading to a decrease in the production of these carbohydrates. This can potentially slow down the growth and spread of cancer cells. In addition, Fanolesomab Biosimilar can also be used as a diagnostic tool to detect the presence of FUT-4 in cancer cells, helping with early detection and treatment.
Fanolesomab Biosimilar has a wide range of applications in cancer research. Its ability to target and inhibit the FUT-4 protein makes it a valuable tool for studying the role of this protein in cancer development and progression. It can also be used to screen potential therapeutic agents that target FUT-4, as well as to evaluate the effectiveness of these agents.
In addition, Fanolesomab Biosimilar can be used in diagnostic assays to detect the presence of FUT-4 in cancer cells. This can aid in the early detection and diagnosis of various types of cancer, such as breast, lung, and colon cancer. It can also be used to monitor the response to treatment and track the progression of the disease.
Furthermore, Fanolesomab Biosimilar has potential therapeutic applications. As a biosimilar version of the original Fanolesomab, it has the potential to be developed into a therapeutic antibody for the treatment of FUT-4 positive cancers. This could provide a targeted and more effective treatment option for cancer patients.
In conclusion, Fanolesomab Biosimilar is a chimeric monoclonal antibody that targets the FUT-4 protein. Its structure and function are similar to the original Fanolesomab, but it is designed for research purposes. Its main activity is to inhibit the function of FUT-4, which has implications in cancer development and progression. Fanolesomab Biosimilar has a wide range of applications in cancer research, including as a diagnostic tool, a research tool, and a potential therapeutic agent.
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