Skip to main content
Contact +1 (919) 234-1277

🚀 Special Offer🚀Get 25% off on your bioreagent online order (except Micelles and Nanodiscs), with the code: PROTEOSHOP25

📢 New ! Accelerate your Antibody Development with Ready-to-use Stable Cell Pools

Explore Now
Nycodenz AG® Nycodenz AG® XtenCHO ™ Race Starter kit XtenCHO ™ Race Starter kit
View all Products

Human Gastricsin(PGII),PGC Recombinant Protein

Reference:
size

100ug, 20ug, 50ug
Brand

ProteoGenix
Product type

Recombinant Proteins
Host Species

Mammalian cells
Applications

Elisa, WB
Tags:
Specification
Documents
Publications
Reviews
Product nameHuman Gastricsin(PGII),PGC Recombinant Protein
Uniprot IDP20142
Uniprot linkhttp://www.uniprot.org/uniprot/P20142
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
SequenceMKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAAGSHHHHHH
Molecular weight43.33 kDa
Protein delivered with Tag?Yes
Purity estimated90%
BufferPBS, pH 7.5
FormFrozen
Delivery conditionDry Ice
Delivery lead time in business days5-7
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesMammalian cells
Fragment TypeFull-length
Spec:NCBI Gene AliasesPGC
Spec:SwissProtIDP20142.1
NCBI Reference P20142
Aliases /SynonymsPepsinogen C, Gastricsin, PGC
ReferencePX-P3001
NoteFor research use only
Datasheet Download
MSDS Download

Publication

  • 1: Kumar S, Kumari N, Mittal RD, Ghoshal UC. Pepsinogen-II 100 bp ins/del gene_x000D_ polymorphism and its elevated circulating levels are associated with gastric_x000D_ cancer, particularly with Helicobacter pylori infection and intestinal_x000D_ metaplasia. Gastric Cancer. 2016 Jul;19(3):808-16. doi:_x000D_ 10.1007/s10120-015-0550-8. Epub 2015 Oct 20. PubMed PMID: 26486507.
    • _x000D_ _x000D_ _x000D_
  • 2: He C, Xu Q, Tu H, Sun L, Gong Y, Liu J, Yuan Y. Polymorphic rs9471643 and_x000D_ rs6458238 upregulate PGC transcription and protein expression in overdominant or _x000D_ dominant models. Mol Carcinog. 2016 May;55(5):586-99. doi: 10.1002/mc.22305. Epub_x000D_ 2015 Apr 7. PubMed PMID: 25857852.
    • _x000D_ _x000D_ _x000D_
  • 3: He CY, Sun LP, Xu Q, Liu JW, Jiang JY, Dong NN, Yuan Y. PGC TagSNP and its_x000D_ interaction with H. pylori and relation with gene expression in susceptibility to_x000D_ gastric carcinogenesis. PLoS One. 2014 Dec 31;9(12):e115955. doi:_x000D_ 10.1371/journal.pone.0115955. eCollection 2014. PubMed PMID: 25551587; PubMed_x000D_ Central PMCID: PMC4281127.
    • _x000D_ _x000D_ _x000D_
  • 4: Massarrat S, Haj-Sheykholeslami A, Mohamadkhani A, Zendehdel N, Aliasgari A,_x000D_ Rakhshani N, Stolte M, Shahidi SM. Pepsinogen II can be a potential surrogate_x000D_ marker of morphological changes in corpus before and after H. pylori eradication._x000D_ Biomed Res Int. 2014;2014:481607. doi: 10.1155/2014/481607. Epub 2014 Jun 17._x000D_ PubMed PMID: 25028655; PubMed Central PMCID: PMC4083213.
    • _x000D_ _x000D_ _x000D_
  • 5: Yoshida T, Kato J, Inoue I, Yoshimura N, Deguchi H, Mukoubayashi C, Oka M,_x000D_ Watanabe M, Enomoto S, Niwa T, Maekita T, Iguchi M, Tamai H, Utsunomiya H,_x000D_ Yamamichi N, Fujishiro M, Iwane M, Takeshita T, Ushijima T, Ichinose M. Cancer_x000D_ development based on chronic active gastritis and resulting gastric atrophy as_x000D_ assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer._x000D_ Int J Cancer. 2014 Mar 15;134(6):1445-57. doi: 10.1002/ijc.28470. Epub 2013 Oct_x000D_ 3. PubMed PMID: 24009139.
    • _x000D_ _x000D_ _x000D_
  • 6: Cao XY, Jia ZF, Jin MS, Cao DH, Kong F, Suo J, Jiang J. Serum pepsinogen II is_x000D_ a better diagnostic marker in gastric cancer. World J Gastroenterol. 2012 Dec_x000D_ 28;18(48):7357-61. doi: 10.3748/wjg.v18.i48.7357. PubMed PMID: 23326145; PubMed_x000D_ Central PMCID: PMC3544042.
    • _x000D_ _x000D_ _x000D_
  • 7: Tahara T, Shibata T, Okubo M, Yamashita H, Yoshioka D, Yonemura J, Maruyama N,_x000D_ Kamano T, Kamiya Y, Fujita H, Nakagawa Y, Nagasaka M, Iwata M, Yamada H, Nakamura_x000D_ M, Arisawa T, Hirata I. Examination of serum pepsinogen in functional dyspepsia. _x000D_ Hepatogastroenterology. 2012 Nov-Dec;59(120):2516-22. doi: 10.5754/hge10604._x000D_ PubMed PMID: 23178618.
    • _x000D_ _x000D_ _x000D_
  • 8: Zheng KC, Aoki K, Li XQ, Lin SG, Wu BS, Zhong WL, Chen TH, Lin S, You JW, Su_x000D_ C. Serum pepsinogens, gastrin-17 and Helicobacter pylori antibody in the_x000D_ residents of two cities in china with distinct mortality rates of gastric cancer._x000D_ Tohoku J Exp Med. 2012;228(4):289-94. PubMed PMID: 23117263.
    • _x000D_ _x000D_ _x000D_
  • 9: He CY, Sun LP, Gong YH, Xu Q, Dong NN, Yuan Y. Serum pepsinogen II: a_x000D_ neglected but useful biomarker to differentiate between diseased and normal_x000D_ stomachs. J Gastroenterol Hepatol. 2011 Jun;26(6):1039-46. doi:_x000D_ 10.1111/j.1440-1746.2011.06692.x. PubMed PMID: 21303408.
    • _x000D_ _x000D_ _x000D_
  • 10: Sun LP, Gong YH, Dong NN, Wang L, Yuan Y. [Correlation of pepsinogen C (PGC) _x000D_ gene insertion/deletion polymorphism to PGC protein expression in gastric mucosa _x000D_ and serum]. Ai Zheng. 2009 May;28(5):487-92. Chinese. PubMed PMID: 19624876.
    • _x000D_ _x000D_ _x000D_
  • 11: Iijima K, Abe Y, Kikuchi R, Koike T, Ohara S, Sipponen P, Shimosegawa T._x000D_ Serum biomarker tests are useful in delineating between patients with gastric_x000D_ atrophy and normal, healthy stomach. World J Gastroenterol. 2009 Feb_x000D_ 21;15(7):853-9. PubMed PMID: 19230047; PubMed Central PMCID: PMC2653386.
    • _x000D_ _x000D_ _x000D_
  • 12: Sun LP, Zhang Y, Liu YE, Chen W, Yuan Y. [Interaction between an_x000D_ insertion/deletion polymorphism in pepsinogen C and Helicobacter pylori infection_x000D_ in the development of gastric cancer]. Zhonghua Zhong Liu Za Zhi. 2008_x000D_ Sep;30(9):644-8. Chinese. PubMed PMID: 19173902.
    • _x000D_ _x000D_ _x000D_
  • 13: Sun LP, Guo XL, Zhang Y, Chen W, Bai XL, Liu J, Yuan Y. Impact of pepsinogen _x000D_ C polymorphism on individual susceptibility to gastric cancer and its_x000D_ precancerous conditions in a Northeast Chinese population. J Cancer Res Clin_x000D_ Oncol. 2009 Aug;135(8):1033-9. doi: 10.1007/s00432-008-0539-3. Epub 2009 Jan 9._x000D_ PubMed PMID: 19132389.
    • _x000D_ _x000D_ _x000D_
  • 14: Pinto-Correia AL, Pinto D, Pereira D, Rodrigues H, de Sousa JA, Sousa H,_x000D_ Sousa B, Sousa S, Lopes C, Medeiros R. Overall survival in women with breast_x000D_ cancer: the influence of pepsinogen C gene polymorphism. DNA Cell Biol. 2008_x000D_ Jun;27(6):333-6. doi: 10.1089/dna.2007.0713. PubMed PMID: 18447628.
    • _x000D_ _x000D_ _x000D_
  • 15: Parthasarathy G, Maroju NK, Kate V, Ananthakrishnan N, Sridhar MG. Serum_x000D_ pepsinogen I and II levels in various gastric disorders with special reference to_x000D_ their use as a screening test for carcinoma stomach. Trop Gastroenterol. 2007_x000D_ Oct-Dec;28(4):166-70. PubMed PMID: 18416347.

Reviews

There are no reviews yet.

REVIEW YOUR PRODUCT

Be the first to review “Human Gastricsin(PGII),PGC Recombinant Protein”

Your email address will not be published. Required fields are marked *

Related products

Human EGF Recombinant Protein
Receptor

Human EGF Recombinant Protein

PX-P3041 250$
View product

Contact us

Send us a message from the form below

    Cart (0 Items)

    Your cart is currently empty.

    View Products