Skip to main content

Human PD-L2 recombinant protein

Reference: PX-P6014-100
size

100ug

Brand

ProteoGenix

Product type

Recombinant Proteins

Host Species

Mammalian cells

Applications

Elisa, WB

Product nameHuman PD-L2 recombinant protein
Uniprot IDQ9BQ51
Uniprot linkhttps://www.uniprot.org/uniprot/Q9BQ51
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
Molecular weight23.62 kDa
Protein delivered with Tag?C-terminal His Tag
Purity estimated>85% by SDS-PAGE
BufferPBS, pH7.5
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesMammalian cells
Fragment TypeMet1-Thr220
Aliases /SynonymsPDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2
ReferencePX-P6014
NoteFor research use only

Description of Human PD-L2 recombinant protein

General information on Human PD-L2 recombinant protein

Structure

Human PD-L2 recombinant protein is a type I transmembrane glycoprotein and is a member of the B7 family of CD proteins. It consists of a single extracellular immunoglobulin-like domain, a transmembrane domain and a short cytoplasmic tail.

Activity

PD-L2 plays an important role in the regulation of immune responses by binding to its receptor PD-1 on the surface of T cells and B cells. This binding leads to the inhibition of the activation and proliferation of these cells, thus acting as an immune checkpoint protein.

Application

Human PD-L2 recombinant protein is used in antibody-drug target therapy, where it is used to develop antibodies that can bind to PD-L2 and block the PD-L2/PD-1 interaction. This can result in the activation and proliferation of T cells and B cells, thus enhancing the immune response against cancer cells.

Reviews

There are no reviews yet.

REVIEW YOUR PRODUCT

Be the first to review “Human PD-L2 recombinant protein”

Your email address will not be published. Required fields are marked *

Contact us

Send us a message from the form below







    Cart (0 Items)

    Your cart is currently empty.

    View Products