Intetumumab Biosimilar – Anti-ITGAV_ITGB3 mAb – Research Grade

Description of Intetumumab Biosimilar - Anti-ITGAV_ITGB3 mAb - Research Grade

The Structure of Intetumumab Biosimilar

Intetumumab Biosimilar, also known as Anti-ITGAV_ITGB3 monoclonal antibody (mAb), is a therapeutic antibody that is designed to target a specific protein complex on the surface of cancer cells. This biosimilar is a recombinant protein that is produced using advanced biotechnology techniques, making it a highly specific and effective treatment option.

The structure of Intetumumab Biosimilar is based on the original monoclonal antibody, Intetumumab, which was developed to target the integrin complex of ITGAV and ITGB3. The biosimilar version is created by using the same amino acid sequence and structure, but with slight modifications to ensure its safety and efficacy. It is a humanized antibody, meaning that it contains both human and non-human components, making it less likely to cause an immune response in patients.

The Activity of Intetumumab Biosimilar

Intetumumab Biosimilar works by binding to the integrin complex of ITGAV and ITGB3 on the surface of cancer cells. This integrin complex plays a critical role in the growth and spread of cancer cells, making it an ideal therapeutic target. By binding to this complex, Intetumumab Biosimilar prevents the interaction of cancer cells with their surrounding environment, inhibiting their ability to grow and spread.

In addition to its direct anti-

cancer activity, Intetumumab Biosimilar also has immune-modulating effects. It can stimulate the immune system to recognize and attack cancer cells, further enhancing its therapeutic potential. This dual mechanism of action makes Intetumumab Biosimilar a potent and effective treatment option for various types of cancer.

Applications of Intetumumab Biosimilar

Intetumumab Biosimilar has shown promising results in preclinical and clinical studies for the treatment of various types of cancer, including lung, breast, and prostate cancer. It has been shown to be effective in both monotherapy and combination therapy settings, making it a versatile treatment option.

In lung

cancer, Intetumumab Biosimilar has been shown to inhibit the growth and metastasis of cancer cells, leading to improved survival rates in patients. In breast cancer, it has been found to be effective in targeting cancer stem cells, which are responsible for cancer recurrence and resistance to treatment. In prostate cancer, Intetumumab Biosimilar has shown promising results in inhibiting the growth and spread of cancer cells, as well as sensitizing them to other anti- cancer therapies.

Intetumumab Biosimilar is currently being evaluated in clinical trials for the treatment of other types of cancer, such as ovarian, pancreatic, and colorectal cancer. It has also shown potential in treating other diseases, such as fibrosis and inflammatory disorders.

Conclusion

In summary, Intetumumab Biosimilar is a promising therapeutic option for the treatment of various types of cancer. Its specific structure, activity, and dual mechanism of action make it a potent and effective treatment option. With ongoing research and clinical trials, Intetumumab Biosimilar has the potential to improve outcomes for cancer patients and expand its applications to other diseases.

SDS-PAGE for Intetumumab Biosimilar - Anti-ITGAV_ITGB3 mAb

Intetumumab Biosimilar - Anti-ITGAV_ITGB3 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.