Lanerkitug Biosimilar – Anti-CKR-L1 mAb – Research Grade

Reference:
Product nameLanerkitug Biosimilar - Anti-CKR-L1 mAb - Research Grade
SourceCAS: 2839417-54-6
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-CKR-L1, CMKBR8, C-C CKR-8, GPR-CY6, CCR8, CMKBRL2, TER1, CCR-8, Chemokine receptor-like 1, CKRL1, CDw198, GPRCY6, C-C chemokine receptor type 8, CC-CKR-8, CC chemokine receptor CHEMR1
ReferencePX-TA2176-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-lambda2
ClonalityMonoclonal Antibody

Description of Lanerkitug Biosimilar - Anti-CKR-L1 mAb - Research Grade

Lanerkitug Biosimilar: A High-Quality Therapeutic Antibody Targeting CKR-L1

Introduction

Lanerkitug Biosimilar is a highly effective therapeutic antibody that targets CKR-L1, a protein that plays a crucial role in various diseases. This biosimilar is a research-grade version of the original Lanerkitug antibody, designed to provide researchers with a high-quality tool for studying CKR-L1 and its potential therapeutic applications. In this article, we will discuss the structure, activity, and potential applications of Lanerkitug Biosimilar in detail.

Structure of Lanerkitug Biosimilar

Lanerkitug Biosimilar is a monoclonal antibody (mAb) that is produced by cloning and expressing a specific gene sequence in mammalian cells. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains contain a constant region (Fc) and a variable region (Fab), while the light chains only have a variable region. The variable regions of the heavy and light chains together form the antigen-binding site of the antibody, which is responsible for its specificity towards CKR-L1.

Activity of Lanerkitug Biosimilar

Lanerkitug Biosimilar binds specifically to CKR-L1 with high affinity, inhibiting its activity and downstream signaling pathways. CKR-L1 is a chemokine receptor that is overexpressed in various cancers, including lung, breast, and ovarian cancer. It plays a crucial role in cancer progression and metastasis by promoting cell proliferation, invasion, and angiogenesis. By binding to CKR-L1, Lanerkitug Biosimilar blocks its interaction with its ligand, inhibiting the downstream signaling pathways and ultimately preventing cancer cell growth and spread.

Applications of Lanerkitug Biosimilar

Lanerkitug Biosimilar has potential applications in both research and clinical settings. In research, this biosimilar can be used as a tool for studying the role of CKR-L1 in various diseases, particularly cancer. Its high specificity and affinity make it a valuable tool for investigating the mechanism of action of CKR-L1 and its potential as a therapeutic target. In addition, Lanerkitug Biosimilar can be used in preclinical studies to evaluate its efficacy and safety as a potential cancer treatment.

In the clinical setting, Lanerkitug Biosimilar has the potential to be used as a targeted therapy for CKR-L1 overexpressing cancers. By inhibiting CKR-L1 activity, this biosimilar can effectively block cancer cell growth and metastasis, providing a promising treatment option for patients with these types of cancers. Furthermore, since Lanerkitug Biosimilar is a biosimilar of the original Lanerkitug antibody, it has undergone extensive characterization and has been proven to have similar efficacy and safety profiles, making it a reliable and cost-effective alternative to the original antibody.

Conclusion

In summary, Lanerkitug Biosimilar is a high-quality therapeutic antibody that specifically targets CKR-L1. Its structure, activity, and potential applications make it a valuable tool for studying CKR-L1 and its role in various diseases, particularly cancer. With its potential as a targeted therapy for CKR-L1 overexpressing cancers, Lanerkitug Biosimilar holds great promise in improving the treatment options for patients with these types of cancers.

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