Micvotabart Biosimilar – Anti-Cold-insoluble globulin mAb – Research Grade

Reference:
Product nameMicvotabart Biosimilar - Anti-Cold-insoluble globulin mAb - Research Grade
SourceCAS: 2867549-73-1
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-Cold-insoluble globulin, CIG, FN, Fibronectin, FN1
ReferencePX-TA2199-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Micvotabart Biosimilar - Anti-Cold-insoluble globulin mAb - Research Grade

Introduction

Micvotabart Biosimilar is a therapeutic antibody that targets the cold-insoluble globulin (CIG) protein. This biosimilar is a research grade product that has been developed to mimic the structure and function of the original anti-CIG monoclonal antibody (mAb). In this article, we will explore the structure, activity, and potential applications of Micvotabart Biosimilar.

Structure of Micvotabart Biosimilar

Micvotabart Biosimilar is a recombinant monoclonal antibody that is produced using a cell line. It is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains consist of constant and variable regions, while the light chains only have variable regions. These variable regions are responsible for binding to the CIG protein.

The amino acid sequence of Micvotabart Biosimilar has been carefully designed to match that of the original anti-CIG mAb. This ensures that the biosimilar has a similar structure and function to the original antibody.

Activity of Micvotabart Biosimilar

The primary activity of Micvotabart Biosimilar is to bind to the CIG protein with high specificity and affinity. This binding prevents the CIG protein from interacting with its target, which is believed to be involved in the development of cold-related diseases such as cold agglutinin disease and cryoglobulinemia.

In addition to its binding activity, Micvotabart Biosimilar also has effector functions that can help to eliminate CIG-expressing cells. This includes antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). These effector functions can aid in the clearance of CIG-expressing cells and help to alleviate symptoms associated with cold-related diseases.

Applications of Micvotabart Biosimilar

Micvotabart Biosimilar has potential applications in the treatment of cold-related diseases, particularly those involving CIG. It can be used as a therapeutic antibody to target and neutralize the CIG protein, thereby reducing its harmful effects on the body.

In addition, Micvotabart Biosimilar can also be used in research settings to study the role of CIG in various diseases and to develop new treatments for cold-related disorders. Its high specificity and affinity for CIG make it a valuable tool for studying the function and interactions of this protein.

Conclusion

In summary, Micvotabart Biosimilar is a research grade therapeutic antibody that targets the cold-insoluble globulin protein. It has a similar structure and function to the original anti-CIG mAb and is designed to specifically bind to and neutralize CIG. This biosimilar has potential applications in the treatment and research of cold-related diseases and can aid in the development of new therapies for these disorders.

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