Monkeypox virus/MPXV A35R Monoclonal Antibody SAA0287

Reference: PTX18825-100
Product nameMonkeypox virus/MPXV A35R Monoclonal Antibody SAA0287
FormLiquid in PBS buffer, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
BrandProteoGenix
Host speciesMouse
ReactivityMonkeypox virus(MPXV)
ReferencePTX18825
IsotypeIgG2a, kappa
ClonalityMonoclonal Antibody
ImmunogenA35R
Clone NameSAA0287
Protein NameA35R
Target speciesAnti-Monkeypox virus(MPXV) Monoclonal Antibody

Description of Monkeypox virus/MPXV A35R Monoclonal Antibody SAA0287

Monkeypox Virus A35R Monoclonal Antibody

Structure

Monkeypox Virus A35R Monoclonal Antibody is a single, specific antibody produced from a single clone of B cells. It is composed of two heavy chains and two light chains linked by disulfide bonds. The two heavy chains are linked to each other by non-covalent bonds and the light chains are linked to the heavy chains by disulfide bonds.

Activity

Monkeypox Virus A35R Monoclonal Antibody binds to the viral antigen, specifically the A35R protein of the Monkeypox virus. This binding inhibits the virus from entering the host cell and prevents the virus from replicating.

Application

Monkeypox Virus A35R Monoclonal Antibody is used for research purpose only in Monkeypox infections.

Detects Monkeypox virus/MPXV A35R in direct ELISAs.

SDS-PAGE for Monkeypox virus/MPXV A35R Monoclonal Antibody SAA0287

Monkeypox virus/MPXV A35R Monoclonal Antibody SAA0287, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Publication

Zuiani et al., A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease, 2024, Cell 187, 1–11March 14, 2024 https://doi.org/10.1016/j.cell.2024.01.017

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