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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG1, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Nezutatug Biosimilar - Anti-ERBB3 mAb - Research Grade |
|---|---|
| Source | CAS: 2673271-78-6 |
| Species | Human |
| Buffer | 0.01M PBS, pH 7.4 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3 |
| Reference | PX-TA1957 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
Nezutatug Biosimilar – Anti-ERBB3 mAb is a promising therapeutic antibody that targets the ERBB3 protein. This biosimilar is a research grade version of the original antibody, Nezutatug, and has been developed for use in scientific research and drug development.
Nezutatug Biosimilar – Anti-ERBB3 mAb is a monoclonal antibody, meaning it is produced from a single clone of cells. It is a large protein molecule, composed of two heavy chains and two light chains, with a total molecular weight of approximately 150 kDa. The antibody has a Y-shaped structure, with the two arms of the Y binding to the ERBB3 protein.
The main activity of Nezutatug Biosimilar – Anti-ERBB3 mAb is its ability to bind to the ERBB3 protein. ERBB3 is a receptor tyrosine kinase that is involved in cell growth and survival. When Nezutatug Biosimilar – Anti-ERBB3 mAb binds to ERBB3, it blocks the signaling pathway that promotes cell growth, leading to inhibition of tumor growth.
The mechanism of action of Nezutatug Biosimilar – Anti-ERBB3 mAb is similar to that of the original antibody, Nezutatug. The antibody binds to the extracellular domain of ERBB3, preventing its interaction with other proteins and inhibiting downstream signaling pathways. This ultimately leads to reduced cell proliferation, angiogenesis, and metastasis.
Nezutatug Biosimilar – Anti-ERBB3 mAb has potential applications in both basic research and drug development. In basic research, it can be used to study the role of ERBB3 in various cellular processes, such as cell growth and survival. It can also be used to investigate the potential of ERBB3 as a therapeutic target in different types of cancer.
In drug development, Nezutatug Biosimilar – Anti-ERBB3 mAb can be used to develop new treatments for cancers that overexpress ERBB3, such as breast, lung, and ovarian cancer. It can also be used in combination with other therapies to improve treatment outcomes. Additionally, the biosimilar can be used in preclinical studies to evaluate the safety and efficacy of potential ERBB3-targeting drugs.
Compared to the original antibody, Nezutatug Biosimilar – Anti-ERBB3 mAb offers several advantages. Firstly, as a research grade version, it is more affordable and accessible for scientists and researchers. Additionally, the biosimilar has a high level of purity and consistency, ensuring reliable and reproducible results in experiments. It also has a longer shelf life, making it more convenient for long-term studies.
In conclusion, Nezutatug Biosimilar – Anti-ERBB3 mAb is a promising therapeutic antibody with a well-defined structure and mechanism of action. Its ability to target the ERBB3 protein makes it a valuable tool for studying and potentially treating various types of cancer. With its advantages and potential applications, this biosimilar has the potential to make a significant impact in the field of cancer research and drug development.
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