Ocrelizumab Biosimilar – Anti-MS4A1, CD20 mAb – Research Grade

Reference:
Size

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Isotype

IgG1-nd

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Product type

Clonality

Expression system

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Product nameOcrelizumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade
SourceCAS 637334-45-3
SpeciesHumanized
Molecular weight145kDa
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsOcrelizumab,2H7,MS4A1, CD20,anti-MS4A1, CD20
ReferencePX-TA1162
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1-nd
ClonalityMonoclonal Antibody

Description of Ocrelizumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

General information on Anti-MS4A1/CD20(Homo sapiens) (Ocrelizumab) Monoclonal Antibody

Ocrelizumab is a CD20-directed cytolytic antibody, which is suitable for the treatment of patients with relapsed or primary progressive multiple sclerosis. It is a second-generation recombinant humanized monoclonal antibody of isotype IgG1 that can selectively target B lymphocytes expressing CD20 antigen. Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system, which can cause neurological dysfunction. Most patients with MS experience recurrent episodes with functional deterioration, followed by recovery or remission.

Ocrelizumab Biosimilar - Anti-MS4A1, CD20 mAb binds to Human CD20/MS4A1 recombinant protein in indirect ELISA Assay

Immobilized Human CD20/MS4A1 recombinant protein (cat. No.PX-P6274) at 0.5µg/mL (100µL/well) can bind to Ocrelizumab Biosimilar - Anti-MS4A1, CD20 mAb (cat. No.PX-TA1162) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

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