Recombinant Human DPF2 Protein, N-His-SUMO & C-Strep
Origin species
Human
Expression system
Prokaryotic expression
Molecular weight
25.12 kDa
Buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Form
Liquid
Delivery condition
Dry Ice
Delivery lead time in business days
3-5 days if in stock; 3-5 weeks if production needed
Storage condition
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand
Arovia
Host species
Escherichia coli (E.coli)
Fragment Type
Glu290-Ser391
Aliases /Synonyms
Protein requiem, BAF45D, Zinc finger protein ubi-d4, BRG1-associated factor 45D, REQ, DPF2, UBID4, Apoptosis response zinc finger protein, D4, zinc and double PHD fingers family 2
Reference
ARO-P11707
Note
For research use only.
Description of Recombinant Human DPF2 Protein, N-His-SUMO & C-Strep
Recombinant Human DPF2 Protein: Structure, Activity, and Application
Introduction
Recombinant proteins are proteins that are produced through genetic engineering techniques, where a specific gene is inserted into a host organism, such as bacteria or yeast, to produce large quantities of the desired protein. Recombinant proteins have become essential tools in various fields of research, including biotechnology, medicine, and diagnostics.
Structure of Recombinant Human DPF2 Protein
The Recombinant Human DPF2 Protein is a 147 kDa protein that belongs to the D4, zinc finger-containing protein family. It is encoded by the DPF2 gene, located on chromosome 8 in humans. The protein consists of 1273 amino acids and contains two conserved domains: the C2H2-type zinc finger domain and the PHD-type zinc finger domain.
The C2H2-type zinc finger domain is responsible for DNA binding, while the PHD-type zinc finger domain is involved in protein-protein interactions. These two domains play a crucial role in the function of Recombinant Human DPF2 Protein.
Activity of Recombinant Human DPF2 Protein
Recombinant Human DPF2 Protein is a transcriptional co-activator that regulates gene expression by binding to specific DNA sequences and interacting with other proteins. It is a key component of the transcriptional machinery and is involved in various cellular processes, including cell proliferation, differentiation, and development.
Studies have shown that Recombinant Human DPF2 Protein plays a critical role in the regulation of gene expression in different tissues, such as the brain, heart, and skeletal muscle. It has also been linked to several diseases, including cancer and neurological disorders.
Application of Recombinant Human DPF2 Protein
Recombinant Human DPF2 Protein has various applications in both research and clinical settings. Its ability to regulate gene expression makes it a valuable tool in studying the molecular mechanisms of different diseases and identifying potential therapeutic targets.
In addition, Recombinant Human DPF2 Protein has been used in the production of monoclonal antibodies for the diagnosis and treatment of cancer. It has also been used in the development of gene therapy strategies for inherited diseases caused by mutations in the DPF2 gene.
Furthermore, Recombinant Human DPF2 Protein has been used in the production of vaccines as an antigen. Its high immunogenicity makes it an ideal candidate for eliciting an immune response and providing protection against specific diseases.
Conclusion
In summary, Recombinant Human DPF2 Protein is a crucial protein with diverse roles in gene regulation and cellular processes. Its structure, activity, and application make it a valuable tool in various fields of research and medicine. Further studies on this protein may lead to a better understanding of its function and potential therapeutic applications.
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