Recombinant Mouse CADM4 Protein, N-His

Description of Recombinant Mouse CADM4 Protein, N-His

Introduction

The Recombinant Mouse CADM4 Protein is a highly purified and biologically active protein that has been produced using recombinant DNA technology. This protein is a member of the Cell Adhesion Molecule (CADM) family, which plays a crucial role in various cellular processes such as cell adhesion, migration, and signaling. The CADM4 protein is found in various tissues and has been shown to have important functions in the nervous system, immune system, and cancer development.

Structure of Recombinant Mouse CADM4 Protein

The Recombinant Mouse CADM4 Protein is a single-chain glycoprotein with a molecular weight of approximately 50 kDa. It is composed of 415 amino acids and has a predicted isoelectric point of 6.5. The protein contains an extracellular region, a transmembrane domain, and a cytoplasmic tail. The extracellular region of CADM4 contains three immunoglobulin-like domains, which are responsible for the protein’s adhesion properties. The transmembrane domain anchors the protein to the cell membrane, while the cytoplasmic tail interacts with intracellular signaling molecules.

Activity of Recombinant Mouse CADM4 Protein

The Recombinant Mouse CADM4 Protein has been shown to have a wide range of activities in different biological processes. One of its main functions is as a cell adhesion molecule, where it mediates cell-cell interactions through its extracellular domains. This activity is important for the formation and maintenance of tissues, as well as for the regulation of cell migration and invasion. CADM4 has also been found to play a role in immune responses, as it is involved in the adhesion and activation of immune cells such as T cells and natural killer cells.

In addition to its adhesion properties, Recombinant Mouse CADM4 Protein has been shown to have a role in signaling pathways. The cytoplasmic tail of CADM4 interacts with various intracellular proteins, including signaling molecules such as Src and Fyn kinases. This interaction can activate downstream signaling pathways, leading to changes in cell behavior and function. CADM4 has also been implicated in the regulation of cell growth and survival, as well as in the development and progression of cancer.

Application of Recombinant Mouse CADM4 Protein

The Recombinant Mouse CADM4 Protein has a wide range of potential applications in both research and clinical settings. Its role in cell adhesion and signaling makes it a valuable tool for studying various cellular processes, such as tissue development and immune responses. The protein can also be used to investigate the mechanisms of cancer development and progression, as CADM4 has been shown to be dysregulated in various types of cancer.

In addition to its research applications, the Recombinant Mouse CADM4 Protein has potential clinical uses. It has been suggested as a biomarker for certain types of cancer, and its expression levels have been correlated with disease progression and patient survival. CADM4 has also been proposed as a potential therapeutic target for cancer treatment, as blocking its activity has been shown to inhibit tumor growth and metastasis in animal models.

Conclusion

The Recombinant Mouse CADM4 Protein is a versatile and biologically active protein that plays important roles in cell adhesion, signaling, and disease. Its structure, activity, and potential applications make it a valuable tool for studying various biological processes and for potential clinical use. Further research on this protein and its interactions may lead to a better understanding of its functions and potential therapeutic applications.