Recombinant Mouse Gal1/LGALS1 Protein, N-His

Description of Recombinant Mouse Gal1/LGALS1 Protein, N-His

The Structure of Recombinant Mouse Gal1/LGALS1 Protein

Recombinant Mouse Gal1/LGALS1 Protein, also known as Galectin-1, is a member of the galectin family of proteins. It is a small, soluble protein that is composed of 135 amino acids and has a molecular weight of approximately 14.5 kDa. The protein is made up of two distinct domains, the N-terminal domain and the C-terminal domain, which are connected by a flexible linker region.

The N-terminal domain of Recombinant Mouse Gal1/LGALS1 Protein is responsible for its carbohydrate binding activity. It contains a conserved carbohydrate recognition domain (CRD) that is responsible for the binding of specific sugar molecules, such as galactose and N-acetyllactosamine. This domain is highly conserved among galectin proteins and is essential for their biological functions.

The C-terminal domain of Recombinant Mouse Gal1/LGALS1 Protein is responsible for its dimerization and oligomerization. It contains a non-canonical carbohydrate binding site that allows the protein to form dimers and higher-order oligomers. This domain also plays a role in the protein’s ability to interact with other proteins and cell surface receptors.

The Activity of Recombinant Mouse Gal1/LGALS1 Protein

Recombinant Mouse Gal1/LGALS1 Protein is a multifunctional protein with a wide range of biological activities. Its main function is to bind to specific sugar molecules on the surface of cells and extracellular matrix proteins. This binding activity allows the protein to modulate cell-cell and cell-matrix interactions, which are essential for various physiological and pathological processes.

One of the key activities of Recombinant Mouse Gal1/LGALS1 Protein is its role in the regulation of immune responses. The protein has been shown to have both pro- and anti-inflammatory effects, depending on the context. It can promote the activation of immune cells, such as macrophages and T cells, and enhance their functions. At the same time, it can also inhibit the production of pro-inflammatory cytokines and the activation of immune cells, thus exerting anti-inflammatory effects.

In addition to its immune regulatory functions, Recombinant Mouse Gal1/LGALS1 Protein also plays a role in cell proliferation, differentiation, and apoptosis. The protein has been shown to promote the proliferation and survival of various cell types, including immune cells, endothelial cells, and cancer cells. It can also regulate the differentiation of immune cells and promote their maturation into effector cells. Furthermore, Recombinant Mouse Gal1/LGALS1 Protein has been shown to induce apoptosis in cancer cells, making it a potential anti-cancer agent.

The Application of Recombinant Mouse Gal1/LGALS1 Protein

Due to its diverse biological activities, Recombinant Mouse Gal1/LGALS1 Protein has a wide range of potential applications in both basic research and clinical settings. In basic research, the protein can be used as a tool to study the role of galectins in various biological processes, such as immune responses and cancer progression. It can also be used to investigate the specific functions of different galectin family members in a variety of cellular and animal models.

In clinical settings, Recombinant Mouse Gal1/LGALS1 Protein has been investigated as a potential therapeutic agent for various diseases. Its immune regulatory functions make it a promising candidate for the treatment of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. The protein’s ability to promote cell proliferation and survival also makes it a potential therapy for tissue regeneration and repair. Additionally, its anti-cancer effects have led to its investigation as a potential treatment for various types of cancer.

In conclusion, Recombinant Mouse Gal1/LGALS1 Protein is a versatile protein with a unique structure and diverse biological activities. Its role in regulating immune responses, cell proliferation, and apoptosis makes it a promising candidate for various therapeutic applications. Further research on this protein and its functions may lead to the development of novel treatments for a wide range of diseases