Recombinant Mouse IL27RA Protein, N-His

Description of Recombinant Mouse IL27RA Protein, N-His

Introduction

Recombinant Mouse IL27RA Protein, also known as Interleukin-27 receptor subunit alpha, is a protein that plays a crucial role in the immune system. It is a member of the IL-6 receptor family and is involved in the regulation of inflammatory responses and immune cell differentiation. This protein has been extensively studied and has shown promising potential in various applications, making it a valuable tool in the field of biotechnology and medicine.

Structure

The Recombinant Mouse IL27RA Protein is a transmembrane protein consisting of 520 amino acids. It has a molecular weight of approximately 57 kDa and is composed of three domains: an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain contains two fibronectin type III domains and a cytokine receptor homology domain, which is responsible for binding to its ligand, IL-27. The transmembrane domain anchors the protein to the cell membrane, while the intracellular domain is involved in signal transduction.

Activity

The primary function of Recombinant Mouse IL27RA Protein is to act as a receptor for IL-27, a cytokine produced by activated immune cells. Upon binding to IL-27, the protein forms a complex with another receptor subunit, IL-6ST, and initiates a signaling cascade that regulates the activity of various immune cells. This signaling pathway plays a critical role in the development and function of T cells, B cells, and natural killer cells. Additionally, Recombinant Mouse IL27RA Protein has been shown to have anti-inflammatory properties and can suppress the activity of pro-inflammatory cytokines, making it a potential therapeutic target for various inflammatory diseases.

Application

The unique structure and activity of Recombinant Mouse IL27RA Protein make it a valuable tool in various applications, including research, diagnostics, and therapeutics. Its ability to regulate immune cell activity makes it a useful target for studying immune responses and developing new treatments for immune-related diseases. This protein has also been used in diagnostic tests to detect the presence of IL-27 and its receptor in patient samples, providing valuable information for disease diagnosis and monitoring.

Research

Recombinant Mouse IL27RA Protein has been extensively used in research to study the role of IL-27 signaling in various diseases and conditions. Its ability to regulate immune cell activity has been studied in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis, as well as in cancer and infectious diseases. Researchers have also used this protein to develop animal models for studying these diseases and testing potential treatments.

Diagnostics

The detection of IL-27 and its receptor is essential in diagnosing and monitoring various diseases. Recombinant Mouse IL27RA Protein has been used in diagnostic tests to detect the presence of these proteins in patient samples. This information can aid in the diagnosis and treatment of diseases such as cancer, autoimmune disorders, and infectious diseases.

Therapeutics

The potential therapeutic applications of Recombinant Mouse IL27RA Protein are vast. Its ability to regulate immune cell activity and suppress inflammation makes it a potential treatment for various diseases, including autoimmune disorders, cancer, and infectious diseases. Researchers are also exploring the use of this protein in combination with other therapies to enhance their effectiveness.

Conclusion

In conclusion, Recombinant Mouse IL27RA Protein is a crucial protein in the immune system, playing a significant role in regulating immune cell activity and suppressing inflammation. Its unique structure and activity make it a valuable tool in research, diagnostics, and therapeutics. Further studies on this protein and its potential applications may lead to the development of new