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Reflocibart Biosimilar – Anti-VRF mAb – Research Grade

Reference:
Size

100ug, 1MG

Brand

ProteoGenix

Isotype

IgG4, kappa

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

XtenCHO

Applications

Elisa

Product nameReflocibart Biosimilar - Anti-VRF mAb - Research Grade
SourceCAS: 2642578-92-3
Origin speciesHumanized
Expression systemXtenCHO
Purity>95% by SDS-PAGE.
Buffer0.01M PBS, pH 7.4.
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
ReferencePX-TA2134
NoteFor research use only. Not suitable for human use.
IsotypeIgG4-kappa
ClonalityMonoclonal Antibody

Description of Reflocibart Biosimilar - Anti-VRF mAb - Research Grade

Introduction

Reflocibart Biosimilar – Anti-VRF mAb – Research Grade is a novel therapeutic antibody that has shown promising results in the treatment of viral respiratory infections. This biosimilar is a monoclonal antibody (mAb) that specifically targets the viral receptor factor (VRF) and has the potential to revolutionize the treatment of respiratory infections.

Structure of Reflocibart Biosimilar

Reflocibart Biosimilar is a recombinant humanized monoclonal antibody that is produced using advanced biotechnology techniques. It is a fully human antibody, meaning that it is derived from human cells and has a high affinity and specificity for its target. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains are made up of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains consist of two constant domains (CL and CL2) and one variable domain (VL). The variable domains are responsible for binding to the target, while the constant domains provide stability and effector functions.

Activity of Reflocibart Biosimilar

Reflocibart Biosimilar works by specifically targeting the viral receptor factor (VRF) on the surface of respiratory viruses. VRF is a key protein involved in viral entry and infection, making it an ideal therapeutic target for the treatment of respiratory infections. The antibody binds to VRF with high affinity and blocks its interaction with the host cells, preventing viral entry and subsequent infection. This mechanism of action effectively neutralizes the virus and prevents its replication, thereby reducing the severity and duration of the infection.

Application of Reflocibart Biosimilar

Reflocibart Biosimilar has shown promising results in preclinical studies and is currently being evaluated in clinical trials for the treatment of respiratory infections caused by various viruses, including influenza, respiratory syncytial virus (RSV), and coronavirus (COVID-19). The antibody has also demonstrated efficacy against emerging viral strains, making it a potential universal treatment for respiratory infections.

Benefits of Reflocibart Biosimilar

As a biosimilar, Reflocibart offers several advantages over traditional antibody therapies. It has a well-defined structure and mechanism of action, making it a safe and effective treatment option. Additionally, being a fully human antibody, it has a reduced risk of immunogenicity and can be administered repeatedly without causing adverse reactions. The biosimilar also has a longer half-life compared to other antibodies, allowing for less frequent dosing.

Conclusion

In conclusion, Reflocibart Biosimilar – Anti-VRF mAb – Research Grade is a promising therapeutic antibody that specifically targets the viral receptor factor and has the potential to revolutionize the treatment of respiratory infections. Its well-defined structure, mechanism of action, and potential for universal efficacy make it a highly desirable treatment option. With ongoing clinical trials, this biosimilar has the potential to improve the lives of millions of people affected by respiratory infections worldwide.

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