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| Size | 100µg, 1MG |
|---|---|
| Isotype | IgG1 |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | VAK-694 Biosimilar - Anti-Binetrakin mAb - Research Grade |
|---|---|
| Source | VAK-694, NVP-VAK-694 |
| Species | Humanized |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-Binetrakin,B-cell stimulatory factor 1,Pitrakinra,Lymphocyte stimulatory factor 1,IL-4,BSF-1,IL4,Interleukin-4,VAK-694, NVP-VAK-694 |
| Reference | PX-TA1911 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1 |
| Clonality | Monoclonal Antibody |
VAK-694 Biosimilar, also known as Anti-Binetrakin mAb, is a novel therapeutic antibody that is currently being developed as a biosimilar to the original Binetrakin monoclonal antibody. This biosimilar is intended to provide a more cost-effective and accessible treatment option for patients with various diseases and conditions.
VAK-694 Biosimilar is a recombinant humanized monoclonal antibody, meaning it is produced using genetic engineering techniques to create a human-like antibody. It is composed of two identical heavy chains and two identical light chains, each with a unique amino acid sequence. These chains are connected by disulfide bonds and together form the Y-shaped structure characteristic of antibodies.
The variable regions of VAK-694 Biosimilar are responsible for its specificity and binding to its target, while the constant regions determine its effector functions. The amino acid sequence of VAK-694 Biosimilar has been carefully designed to closely match that of the original Binetrakin antibody, ensuring its similarity in structure and function.
VAK-694 Biosimilar is a potent inhibitor of Binetrakin, a protein involved in various signaling pathways that regulate cell growth, survival, and differentiation. Binetrakin is known to be overexpressed in many types of cancer, making it a promising therapeutic target.
By binding to Binetrakin, VAK-694 Biosimilar blocks its activity and prevents it from promoting cancer cell growth. This mechanism of action has been demonstrated in preclinical studies, where VAK-694 Biosimilar has shown significant anti-tumor activity in various cancer models.
In addition to its anti-tumor effects, VAK-694 Biosimilar may also have potential in the treatment of autoimmune and inflammatory diseases. Binetrakin has been implicated in the pathogenesis of these conditions, and by inhibiting its activity, VAK-694 Biosimilar may help to reduce inflammation and disease progression.
VAK-694 Biosimilar is currently in the research phase of development, with preclinical studies showing promising results. It is being investigated for its potential as a treatment for various types of cancer, including breast, lung, and colon cancer, as well as autoimmune and inflammatory diseases such as rheumatoid arthritis and psoriasis.
The biosimilar nature of VAK-694 Biosimilar means that it has the potential to offer a more affordable treatment option for patients, making it more accessible to those in need. It is also expected to have a similar safety and efficacy profile to the original Binetrakin antibody, providing a reliable and effective treatment option.
In conclusion, VAK-694 Biosimilar is a novel therapeutic antibody that has the potential to become a valuable treatment option for a range of diseases and conditions. Its carefully designed structure and potent activity against the therapeutic target Binetrakin make it a promising candidate for further development. As research continues, VAK-694 Biosimilar may offer new hope for patients in need of effective and affordable treatments.
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