Antibody production
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Antibody productionIs genetic immunization a one-size-fits-all solution to accelerate polyclonal antibody generation?
Philippe Funfrock
Polyclonal antibodies are valuable tools for research as secondary reagents or therapy as antivenom drugs. However, their production has largely remained unchanged in the past decades relying on time-consuming, non-scalable,…
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Can antibody therapeutics serve as effective tools to treat and alleviate aggressive rare diseases?
Although rare diseases are characterized by a generalized low incidence in the global population, collectively, over 7,000 different conditions affect… Read More
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What makes antibody therapeutics uniquely fitted to fight autoimmune disorders?
Autoimmune disorders afflict almost 10% of the global population, with a particular incidence in young and middle-aged women. Despite the… Read More
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How advanced monoclonal antibody generation methods are improving conventional envenoming treatments
Snakebite envenoming has been on WHO’s priority list of neglected tropical diseases since 2017. Due to the complexity and variability… Read More
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What are the leading monoclonal antibody treatments for cancer?
Arresting cancer progression has evolved from the use of unspecific chemotherapies with serious adverse effects to the adoption of antibody-based… Read More
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“Cell-based phage display is helping us isolate more biologically relevant antibodies” – Interview with Dr. Mohamed Alfaleh (King Abdulaziz University)
Dr. Mohamed Alfaleh is an assistant professor at King Abdulaziz University (Faculty of Pharmacy, Jeddah, Saudi Arabia). Pharmacist by training,… Read More
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Can a single amino acid mutation change the course of the COVID-19 pandemic?
Viruses mutate in the course of an epidemic as a result of selective pressure or genetic drift. Resulting mutations may… Read More
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Essential antibody library generation and display technologies for the discovery of new reagents and biopharmaceuticals
Library generation is a vital first step in any antibody phage display project for therapeutic applications and others. Libraries… Read More
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Can successful anticancer immunotherapies change the course of the COVID-19 disease?
A recent study revealed the hidden parallelisms in our organism’s response to cancer and COVID-19. Despite the marked differences between… Read More
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Why phage display for monoclonal antibody production remains an unrivaled technology
Phage display technology revolutionized antibody discovery. By coupling the structural simplicity of phages with the fast replication and high turnover… Read More
