Artificial Intelligence Meets Wet Lab

What AI brings to your projects

At ProteoGenix, our AI leverages ~10 billion sequences and continuously improves with each project. Concretely, it enables:

• Accelerate timelines by up to 80% by prioritizing the best candidates
• Reduce costs by focusing resources on the most promising candidates from day one
• Explore the impossible: access sequence spaces unreachable by classical methods
• Simultaneously optimize affinity, stability, manufacturability, and immunogenicity

Our approach: the AI-Wet Lab loop

Our methodology follows a continuous iterative cycle.

AI proposes optimized variants, we produce and test them in the lab, and experimental results feed back into the model to refine subsequent recommendations. This loop ensures every prediction is validated against real data, continuously improving our models with each project.

• Analysis – We define your objectives, constraints, and optimization strategy based on available data.
• Design – AI explores the sequence space and generates variants optimized for your specific criteria.
• Production – Selected candidates are expressed and purified in our facilities.
• Testing – We characterize each variant with relevant assays to measure critical properties.

Results from testing inform the next AI cycle, creating a feedback loop that accelerates development while minimizing risk.

AI, yes… but used intelligently

AI alone isn’t enough. To deliver reliable results, it must be grounded in quality data, validated experimentally, and interpreted by experts who master both IA and biology. At ProteoGenix, we’ve built the infrastructure to make AI truly effective:

• Data trained on ~10 billion sequences. Our models learn exclusively on high-quality experimental results we’ve produced and verified in our own labs.
• Structural analysis guides every design. We systematically integrate 3D structure and antigen interactions—unlike most AI tools working blind on sequences alone.
• Rigorous sequence analysis at every step. Our bioinformatics team ensures sequence integrity and catches potential issues before production.
• Every key prediction is tested. Our wet lab validates recommendations and feeds results back to improve future predictions.
• Expert interpretation bridges AI and biology. Our team turns AI scores into actionable decisions: which variants to produce, which tests to run, which trade-offs to accept.

Our AI services

ProteoGenix provides advanced artificial intelligence tools specifically designed to optimize every step of antibody development:

• Optimization: improvement of biophysical properties and stability of your candidates
• Affinity Maturation: affinity enhancement while preserving critical properties
• Developability: reduction of aggregation, instability, and production difficulties risks
• Humanization: conversion of sequences into human sequences to reduce immunogenicity
• Speciation: conversion of sequences from species A to species B while preserving antibody properties