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Biciromab Biosimilar – Anti-Fibrin II beta chain,fibrin mAb – Research Grade

Reference:
Size

100ug, 1MG

Isotype

Fab'-G1-kappa

Brand

ProteoGenix

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

Mammalian cells

Applications

Elisa, WB

Product nameBiciromab Biosimilar - Anti-Fibrin II beta chain,fibrin mAb - Research Grade
SourceCAS 138783-13-8
SpeciesMus musculus
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsBiciromab,Indium (111In) biciromab,T2G1,Fibrin II beta chain,fibrin,anti-Fibrin II beta chain,fibrin
ReferencePX-TA1091
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeFab'-G1-kappa
ClonalityMonoclonal Antibody

Description of Biciromab Biosimilar - Anti-Fibrin II beta chain,fibrin mAb - Research Grade

Introduction

Biciromab Biosimilar, also known as Anti-Fibrin II beta chain or fibrin mAb, is a monoclonal antibody that has been developed as a biosimilar to the original drug, Biciromab. This biosimilar has been designed to target the fibrin II beta chain, which is a key component of the blood clotting process. In this article, we will discuss the structure, activity, and potential applications of Biciromab Biosimilar in the field of research.

Structure of Biciromab Biosimilar

Biciromab Biosimilar is a monoclonal antibody that is produced using recombinant DNA technology. It is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The antibody has a molecular weight of approximately 150 kDa and belongs to the IgG1 subclass. The heavy and light chains are composed of variable and constant regions, which determine the specificity and effector functions of the antibody, respectively.

Activity of Biciromab Biosimilar

Biciromab Biosimilar specifically targets the fibrin II beta chain, which is a component of the fibrinogen molecule. Fibrinogen is a protein that is involved in blood clotting and is converted into fibrin during the clotting process. The fibrin II beta chain is responsible for the polymerization of fibrin, which forms the structural framework of blood clots. By targeting this specific component, Biciromab Biosimilar inhibits the formation of blood clots, making it a potential therapeutic option for conditions associated with excessive clotting, such as deep vein thrombosis and pulmonary embolism.

Potential Applications of Biciromab Biosimilar

Biciromab Biosimilar has the potential to be used in a variety of research applications due to its ability to target the fibrin II beta chain. One potential application is in the study of blood clotting disorders. By using Biciromab Biosimilar, researchers can better understand the role of the fibrin II beta chain in the clotting process and potentially develop new treatments for clotting disorders.

Another potential application of Biciromab Biosimilar is in the field of cardiovascular research. The formation of blood clots is a major contributor to cardiovascular diseases, such as heart attacks and strokes. By targeting the fibrin II beta chain, Biciromab Biosimilar may have a role in preventing or treating these conditions.

In addition, Biciromab Biosimilar can also be used in cancer research. Tumors often produce factors that promote blood clotting, which can contribute to the spread of cancer cells. By inhibiting the fibrin II beta chain, Biciromab Biosimilar may be able to prevent or slow down the formation of blood clots in cancer patients.

Conclusion

In summary, Biciromab Biosimilar is a monoclonal antibody that specifically targets the fibrin II beta chain. Its structure, composed of heavy and light chains, allows it to effectively bind to this component and inhibit the formation of blood clots. This biosimilar has the potential to be used in various research applications, including the study of blood clotting disorders, cardiovascular diseases, and cancer. Further research and development of Biciromab Biosimilar may lead to its potential use as a therapeutic option in the future.

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