Datopotamab Biosimilar – Anti-TACSTD2 mAb – Research Grade

Description of Datopotamab Biosimilar - Anti-TACSTD2 mAb - Research Grade

Introduction

Datopotamab Biosimilar, also known as Anti-TACSTD2 mAb, is a promising therapeutic antibody that targets the Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) protein. This biosimilar is currently in the research grade stage and shows great potential in treating various types of cancers.

Structure of Datopotamab Biosimilar

Datopotamab Biosimilar is a monoclonal antibody (mAb) that is produced by recombinant DNA technology. It is a humanized antibody, meaning that it contains both human and mouse components. The antibody has a molecular weight of approximately 150 kDa and consists of two heavy chains and two light chains. The variable regions of the antibody are responsible for its specificity towards the TACSTD2 protein.

Activity of Datopotamab Biosimilar

The main activity of Datopotamab Biosimilar is its ability to bind to the TACSTD2 protein. TACSTD2 is a transmembrane glycoprotein that is overexpressed in various types of cancers, including breast, lung, and colorectal cancer. This protein plays a crucial role in promoting tumor growth and metastasis. By binding to TACSTD2, Datopotamab Biosimilar inhibits its activity and prevents cancer cells from proliferating and spreading.

In addition to its direct binding activity, Datopotamab Biosimilar also has an immune-modulating effect. It can activate the immune system to recognize and attack cancer cells that express TACSTD2. This makes it a promising immunotherapy option for cancer treatment.

Application of Datopotamab Biosimilar

Datopotamab Biosimilar has shown promising results in preclinical studies and is currently being evaluated in clinical trials. Its potential applications include the treatment of various types of cancers that overexpress TACSTD2, such as breast, lung, and colorectal cancer.

In addition, Datopotamab Biosimilar can also be used in combination with other cancer treatments, such as chemotherapy and radiation therapy. Its immune-modulating effect can enhance the effectiveness of these treatments and potentially reduce the risk of cancer recurrence.

Future prospects

Datopotamab Biosimilar has the potential to become a game-changer in the field of cancer treatment. Its specific targeting of TACSTD2 and immune-modulating activity make it a promising therapy for various types of cancers. With ongoing clinical trials, we can expect to see more data on its efficacy and safety, which will pave the way for its approval and commercialization.

Conclusion

In conclusion, Datopotamab Biosimilar is a promising therapeutic antibody that targets the TACSTD2 protein in cancer cells. Its unique structure and activity make it a potential treatment option for various types of cancers. With ongoing research and clinical trials, we can hope to see this biosimilar being used in the near future to improve the outcomes of cancer patients.

SDS-PAGE for Datopotamab Biosimilar - Anti-TACSTD2 mAb

Datopotamab Biosimilar - Anti-TACSTD2 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.