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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG2a, lambda |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Grisnilimab Biosimilar - Anti-CD7 mAb - Research Grade |
|---|---|
| Source | CAS 2367001-70-3 |
| Species | Mus musculus |
| Purity | >85% |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | Grisnilimab,GRISNILIMAB,IMMUNOGLOBULIN G2A-LAMBDA, ANTI-(CD7 (CD7 ANTIGEN (P41),GP40, LEU-9, TP41, TP40)), MUS MUSCULUSMONOCLONAL ANTIBOD (GRISNILIMAB), IMMUNOGLOBULIN G2A, ANTI-(HUMAN CD7 ANTIGEN) (MUS MUSCULUS MONOCLONAL WT1 .GAMMA.2A-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL WT1 .LAMBDA.-CHAIN, DIMER,CD7,anti-CD7 |
| Reference | PX-TA1672 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG2a,Lambda |
| Clonality | Monoclonal Antibody |
Introduction to Grisnilimab Biosimilar – A Promising Anti-CD7 mAb for Research Use Grisnilimab Biosimilar, also known as Anti-CD7 mAb, is a monoclonal antibody that has been developed as a biosimilar of the original Grisnilimab, a therapeutic antibody targeting CD7. CD7 is a cell surface protein that is expressed on T cells, natural killer (NK) cells, and hematopoietic stem cells. As a biosimilar, Grisnilimab Biosimilar is designed to have similar structure, activity, and application as the original Grisnilimab, providing researchers with a more cost-effective and accessible option for their studies.
Structure of Grisnilimab Biosimilar – A Monoclonal Antibody with High Specificity for CD7 Grisnilimab Biosimilar is a chimeric monoclonal antibody, meaning it is composed of both human and mouse components. It consists of two heavy chains and two light chains, each with a variable region that recognizes and binds to CD7. The variable regions are derived from the original Grisnilimab, ensuring high specificity for CD7. The constant regions of the antibody are human, reducing the risk of immune reactions in research subjects.
Mechanism of Action – How Grisnilimab Biosimilar Targets CD7 for Therapeutic Use Grisnilimab Biosimilar works by binding to CD7 on the surface of T cells, NK cells, and hematopoietic stem cells. This binding prevents the activation and proliferation of these cells, leading to a decrease in their numbers. This is beneficial in conditions where these cells are overactive, such as in autoimmune diseases and certain types of cancer. Grisnilimab Biosimilar also has the ability to induce antibody-dependent cellular cytotoxicity (ADCC), where immune cells recognize and destroy cells bound by the antibody.
Title: Applications of Grisnilimab Biosimilar – A Versatile Tool for Research on CD7 Grisnilimab Biosimilar has a wide range of potential applications in research, particularly in the study of CD7. Its ability to specifically target CD7 makes it a valuable tool for understanding the function of this protein in various diseases and conditions. It can also be used to investigate the role of CD7 in immune responses, as well as in the development and progression of cancers. Additionally, Grisnilimab Biosimilar can be used to screen for potential therapeutic targets and to evaluate the efficacy of new treatments.
Advantages of Using Grisnilimab Biosimilar in Research – Cost-Effective and Accessible Compared to the original Grisnilimab, Grisnilimab Biosimilar offers several advantages for researchers. Its lower cost makes it a more affordable option for studies with a limited budget. It is also more accessible, as it does not require specialized manufacturing techniques and can be produced in larger quantities. This makes it easier to obtain for researchers who may not have access to the original Grisnilimab.
Conclusion – Grisnilimab Biosimilar – A Valuable Addition to the Researcher’s Toolbox In summary, Grisnilimab Biosimilar is a chimeric monoclonal antibody that has been developed as a biosimilar of the original Grisnilimab. It has a similar structure and activity, specifically targeting CD7 and inhibiting the activation and proliferation of T cells, NK cells, and hematopoietic stem cells. Its applications in research are vast, and its advantages over the original Grisnilimab make it a valuable tool for studying CD7 and its role in various diseases and conditions. With its potential to contribute to the development of new treatments, Grisnilimab Biosimilar is a promising addition to the researcher’s toolbox.
Grisnilimab Biosimilar - Anti-CD7 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
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