Nipah virus(HeV) -Fusion glycoprotein F0 recombinant protein

Reference: PX-P6240-100
Product nameNipah virus(HeV) -Fusion glycoprotein F0 recombinant protein
Uniprot IDQ9IH63
Origin speciesNipah virus(HeV)
Expression systemEukaryotic expression
Molecular weight57.71 kDa
Protein delivered with Tag?C-Terminal His Tag
Purity estimated>85% by SDS-PAGE
BufferLyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesMammalian cells
ApplicationsELISA,WB
Fragment TypeIle27-Ser493
Aliases /SynonymsFusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Nipah Virus (NiV) / Hendra Virus (HeV)
ReferencePX-P6240
NoteFor research use only

Description of Nipah virus(HeV) -Fusion glycoprotein F0 recombinant protein

Nipah Virus (HeV) Structure

Nipah virus (HeV) is a negative-sense, single-stranded RNA virus belonging to the family Paramyxoviridae. It is composed of a nucleocapsid core surrounded by a lipid envelope and a matrix protein. Its genome is 15,000 nucleotides in length, and it encodes six structural proteins and four non-structural proteins.

Nipah Virus (HeV) Activity

The activity of the Nipah virus (HeV) is mediated by its structural proteins. The F and G glycoproteins form the virus’ fusion complex, allowing it to enter host cells and fuse with the host cell membrane. The matrix protein M is involved in viral assembly and budding from the host cell. The nucleocapsid protein N is involved in the formation of the viral ribonucleoprotein complex.

Nipah Virus (HeV) Drug Target

The F fusion glycoprotein F0 is a potential drug target for Nipah virus (HeV). This protein is essential for the virus’ entry into host cells and is a promising target for vaccine and therapeutic strategies. Inhibition of the F0 glycoprotein could prevent the virus from entering host cells, thus preventing infection.

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