Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Form
Liquid
Delivery condition
Dry Ice
Delivery lead time in business days
3-5 days if in stock; 3-5 weeks if production needed
Storage condition
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand
Arovia
Host species
Escherichia coli (E.coli)
Fragment Type
Met156-Asp275
Aliases /Synonyms
NTKLBP1, NTKL-BP1, SCYL1-binding protein 1, SCYL1BP1, SCY1-like 1-binding protein 1, GORAB, NTKL-binding protein 1, SCYL1-BP1, hNTKL-BP1, RAB6-interacting golgin, N-terminal kinase-like-binding protein 1
Reference
ARO-P11290
Note
For research use only.
Description of Recombinant Human GORAB Protein, N-His
Introduction
Recombinant Human GORAB Protein, also known as Golgin-245-Related Protein, is a highly purified and biologically active protein that is produced through recombinant DNA technology. This protein plays a crucial role in regulating the structure and function of the Golgi apparatus, a cellular organelle involved in protein processing and trafficking.
Structure of Recombinant Human GORAB Protein
Recombinant Human GORAB Protein is a 21 kDa protein consisting of 189 amino acids. It contains a single N-terminal transmembrane domain and a C-terminal coiled-coil domain, which is essential for its function in maintaining the structure of the Golgi apparatus.
Activity of Recombinant Human GORAB Protein
The main function of Recombinant Human GORAB Protein is to regulate the structure and dynamics of the Golgi apparatus. It does so by interacting with other Golgi-associated proteins, such as GM130 and GRASP65, to form a protein complex that is essential for maintaining the structural integrity of the Golgi apparatus. This protein complex also plays a role in the organization and positioning of the Golgi within the cell.
Furthermore, Recombinant Human GORAB Protein has been shown to be involved in the transport of proteins and lipids within the Golgi apparatus, as well as in the formation of transport vesicles that are responsible for delivering cargo to their final destinations within the cell.
Application of Recombinant Human GORAB Protein
The unique structure and activity of Recombinant Human GORAB Protein make it a valuable tool for various research purposes. Some of its applications include:
Study of Golgi apparatus structure and function: Recombinant Human GORAB Protein can be used to study the role of the Golgi apparatus in protein processing and trafficking, as well as its involvement in various cellular processes.
Drug discovery and development: As the Golgi apparatus is a target for many diseases, Recombinant Human GORAB Protein can be used to screen potential drugs that can modulate its activity and potentially treat diseases associated with Golgi dysfunction.
Biotechnology and protein engineering: Recombinant Human GORAB Protein can be used to engineer and modify the structure and function of the Golgi apparatus, which can have implications in the production of recombinant proteins and other biotechnological processes.
Conclusion
In summary, Recombinant Human GORAB Protein is a vital component in regulating the structure and function of the Golgi apparatus. Its unique structure and activity make it an important tool for research, drug discovery, and biotechnology. With its multiple applications, this protein continues to contribute to our understanding of cellular processes and has the potential to impact various fields of science and medicine.
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