Recombinant Human JADE1 Protein, N-His

Description of Recombinant Human JADE1 Protein, N-His

The Structure of Recombinant Human JADE1 Protein

Recombinant Human JADE1 Protein is a type of protein that is produced through genetic engineering techniques. It is a member of the JADE family of proteins, which are known to play important roles in cell growth and development.

The structure of Recombinant Human JADE1 Protein is composed of 404 amino acids, with a molecular weight of approximately 45 kDa. It contains several functional domains, including a PHD finger, a bromodomain, and a JADE domain. These domains are responsible for the protein’s ability to interact with other molecules and carry out its biological functions.

The PHD finger domain of Recombinant Human JADE1 Protein is responsible for binding to specific histone modifications, which are important for regulating gene expression. The bromodomain, on the other hand, is involved in recognizing and binding to acetylated lysine residues on histone proteins. This allows the protein to interact with chromatin and regulate gene expression.

The JADE domain of Recombinant Human JADE1 Protein is essential for its interaction with other members of the JADE family, as well as with other proteins involved in chromatin remodeling. This domain also plays a role in the protein’s ability to regulate cell proliferation and differentiation.

The Activity of Recombinant Human JADE1 Protein

Recombinant Human JADE1 Protein is involved in a wide range of cellular processes, including gene expression, chromatin remodeling, and cell growth and differentiation. It is known to act as a transcriptional co-regulator, meaning it can influence the expression of genes by interacting with other proteins and modifying chromatin structure.

One of the main functions of Recombinant Human JADE1 Protein is its role in regulating the activity of transcription factors. By binding to specific histone modifications and interacting with other proteins, it can either activate or repress the transcription of target genes. This allows the protein to control important cellular processes, such as cell proliferation and differentiation.

In addition, Recombinant Human JADE1 Protein has been shown to play a role in chromatin remodeling. It can interact with other proteins involved in chromatin modification, such as histone acetyltransferases and deacetylases, to regulate the accessibility of DNA and control gene expression.

The Application of Recombinant Human JADE1 Protein

Recombinant Human JADE1 Protein has various applications in both basic research and clinical settings. Its role in regulating gene expression and chromatin remodeling makes it a valuable tool for studying cellular processes and understanding disease mechanisms.

In basic research, Recombinant Human JADE1 Protein can be used to study the function of the JADE family of proteins and their role in cell growth and development. It can also be used to investigate the mechanisms of gene expression and chromatin remodeling, as well as their dysregulation in diseases such as cancer.

In clinical settings, Recombinant Human JADE1 Protein has potential as a therapeutic target for diseases that involve abnormal gene expression or chromatin remodeling. It has been linked to various types of cancer, and targeting its activity may provide a new approach for cancer treatment.

In addition, Recombinant Human JADE1 Protein can also be used in diagnostic assays to detect the presence of specific histone modifications or to measure the activity of transcription factors. This can aid in the diagnosis and monitoring of diseases related to gene expression and chromatin remodeling.

In conclusion, Recombinant Human JADE1 Protein is a crucial component in regulating gene expression and chromatin structure. Its unique structure and diverse functions make it a valuable tool for both basic research and clinical applications, with potential for further advancements in understanding and treating diseases.