Recombinant Human SSR1 Protein, N-His

Reference: YHE41001
Product nameRecombinant Human SSR1 Protein, N-His
Origin speciesHuman
Expression systemProkaryotic expression
Molecular weight15.49 kDa
BufferLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
FormLiquid
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandAntibodySystem
Host speciesEscherichia coli (E.coli)
Fragment TypeSer82-Glu198
Aliases /SynonymsTRAPA, TRAP-alpha, Translocon-associated protein subunit alpha, SSR-alpha, SSR1, Signal sequence receptor subunit alpha
ReferenceYHE41001
NoteFor research use only.

Description of Recombinant Human SSR1 Protein, N-His

Introduction

Recombinant Human SSR1 protein is a type of protein that is produced through genetic engineering techniques. This protein is an important tool in the field of biotechnology, as it has many applications in both research and clinical settings. In this article, we will explore the structure, activity, and applications of Recombinant Human SSR1 Protein.

Structure of Recombinant Human SSR1 Protein

Recombinant Human SSR1 Protein is a member of the superfamily of small cytokines known as chemokines. It is encoded by the CXCL12 gene and is composed of 93 amino acids. The amino acid sequence of this protein is highly conserved among different species, indicating its importance in biological processes.

The structure of Recombinant Human SSR1 Protein is characterized by a three-dimensional fold, with a conserved disulfide bond between cysteine residues at positions 7 and 45. This disulfide bond is essential for the protein’s stability and function. The protein also contains a flexible loop region, which is important for its interaction with other molecules.

Activity of Recombinant Human SSR1 Protein

Recombinant Human SSR1 Protein is a chemokine that plays a crucial role in cell signaling and immune response. It acts as a chemoattractant, meaning it attracts certain types of cells to a specific location. This protein binds to its receptor, CXCR4, on the surface of target cells, triggering a cascade of signaling events that lead to cell migration.

In addition to its role in cell migration, Recombinant Human SSR1 Protein also has other activities. It can stimulate the production of cytokines, which are important molecules involved in inflammation and immune response. It also has anti-inflammatory properties, as it can inhibit the production of pro-inflammatory cytokines.

Applications of Recombinant Human SSR1 Protein

Recombinant Human SSR1 Protein has a wide range of applications in both research and clinical settings. One of its main uses is in cell culture studies, where it is used to study cell migration and immune response. This protein is also used in animal models to study the role of chemokines in various diseases.

In the clinical setting, Recombinant Human SSR1 Protein has been investigated as a potential therapeutic agent for various conditions. It has been shown to have potential in treating inflammatory diseases such as rheumatoid arthritis and multiple sclerosis. It has also been studied as a potential treatment for HIV, as it can block the entry of the virus into cells.

Another important application of Recombinant Human SSR1 Protein is in cancer research. This protein has been found to play a role in tumor growth and metastasis, making it a potential target for cancer treatment. Studies have shown that blocking the interaction between Recombinant Human SSR1 Protein and its receptor can inhibit tumor growth and metastasis.

Conclusion

In conclusion, Recombinant Human SSR1 Protein is a key player in cell signaling and immune response. Its structure, activity, and applications make it an important tool in biotechnology and a potential therapeutic agent for various diseases. Further research on this protein may lead to new insights and treatments for a range of conditions.

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