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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG1, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Valanafusp Biosimilar - Anti-INSR mAb - Research Grade |
|---|---|
| Source | CAS 1815583-32-4 |
| Species | Chimeric |
| Purity | >85% |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | Valanafusp,AGT-181, VALANAFUSP ALFA,INSR,anti-INSR |
| Reference | PX-TA1734 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1,Kappa |
| Clonality | Monoclonal Antibody |
Valanafusp Biosimilar – Anti-INSR mAb is a research grade monoclonal antibody (mAb) that specifically targets the insulin receptor (INSR). This biosimilar is a highly effective therapeutic tool for studying the structure, activity, and application of INSR in various biological processes. In this article, we will delve into the details of Valanafusp Biosimilar – Anti-INSR mAb and its potential uses in scientific research.
Valanafusp Biosimilar – Anti-INSR mAb is a recombinant, humanized mAb that is produced using advanced biotechnology techniques. It is composed of two identical heavy chains and two identical light chains, each containing variable and constant regions. The variable regions of the mAb are responsible for binding to the INSR, while the constant regions provide stability and regulate immune responses.
The primary activity of Valanafusp Biosimilar – Anti-INSR mAb is its ability to specifically bind to the INSR with high affinity. This binding leads to the inhibition of insulin signaling, which is crucial for regulating glucose metabolism and other cellular processes. By blocking the INSR, Valanafusp Biosimilar – Anti-INSR mAb can modulate insulin sensitivity and potentially improve insulin resistance in diseases such as diabetes.
Furthermore, Valanafusp Biosimilar – Anti-INSR mAb has been shown to have anti-tumor effects in certain types of cancer. The INSR is overexpressed in many cancer cells, and by targeting it with this mAb, Valanafusp Biosimilar can inhibit tumor growth and promote cell death. This makes it a promising candidate for cancer therapy.
Valanafusp Biosimilar – Anti-INSR mAb has a wide range of applications in scientific research. Its ability to specifically target the INSR makes it a valuable tool for studying the role of this receptor in various biological processes. Some potential applications of this biosimilar include:
1. Investigating insulin resistance and diabetes Insulin resistance is a hallmark of type 2 diabetes and other metabolic disorders. By blocking the INSR, Valanafusp Biosimilar – Anti-INSR mAb can help researchers understand the mechanisms underlying insulin resistance and develop new treatments for these diseases.
2. Studying cancer biology As mentioned earlier, Valanafusp Biosimilar – Anti-INSR mAb has shown promising anti-tumor effects in certain types of cancer. Its ability to specifically target the INSR can provide valuable insights into the role of this receptor in cancer development and progression.
3. Developing new therapies for cancer and other diseases The therapeutic potential of Valanafusp Biosimilar – Anti-INSR mAb extends beyond its use as a research tool. Its ability to inhibit insulin signaling and promote cell death in cancer cells makes it a promising candidate for cancer therapy. Additionally, targeting the INSR with this mAb may have potential applications in other diseases such as polycystic ovary syndrome and acromegaly.
4. Improving insulin sensitivity Insulin resistance is a major contributor to the development of type 2 diabetes and other metabolic disorders. By targeting the INSR, Valanafusp Biosimilar – Anti-INSR mAb has the potential to improve insulin sensitivity and potentially prevent or treat these diseases.
In summary, Valanafusp Biosimilar – Anti-INSR mAb is a highly effective research grade mAb that specifically targets the INSR. Its unique structure and activity make it a valuable tool for studying the role of the INSR in various biological processes. Furthermore, its potential applications in cancer
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