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Nesvacumab Biosimilar – Anti-ANGPT2 mAb – Research Grade

Reference:
Product Image
Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay
Product Image
Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay
Size

100ug, 1MG
Isotype

IgG1-nd
Brand

ProteoGenix
Product type

Primary Antibodies
Clonality

Monoclonal Antibody
Expression system

Mammalian cells
Applications

Elisa, WB
Tags:
Specification
Description
Documents
QC & Validation Data1
Publications
Reviews
Product nameNesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade
SourceCAS 1296818-77-3
SpeciesHomo sapiens
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsNesvacumab,REGN-910,ANGPT2,anti-ANGPT2
ReferencePX-TA1311
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-nd
ClonalityMonoclonal Antibody

Description of Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade

General information on Anti-ANGPT2[Homo sapiens] (Nesvacumab) Monoclonal Antibody

Nesvacumab is investigated for the treatment of Neovascular (Wet) Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME).

Datasheet Download
MSDS Download

Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay

Immobilized Human ANGPT2-Ang2 recombinant protein (cat. No. PX-P6245) at 0.5µg/mL (100µL/well) can bind Nesvacumab Biosimilar - Anti-ANGPT2 mAb (cat. No. PX-TA1311) in indirect ELISA with Goat Anti-human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 16.93M.

Publication

Sim, M., Ohnuki, H., Durell, S. et al. Angiopoietin-2 binds to FGFR2, inhibits FGF-FGFR2 signaling, and delays cutaneous wound healing by inhibiting wound angiogenesis. Angiogenesis 28, 43 (2025). https://doi.org/10.1007/s10456-025-09988-2

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