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Human Chromogranin A Partial [19-457] Recombinant Protein C- His Tag

Reference:
size

100ug, 50ug
Brand

ProteoGenix
Product type

Recombinant Proteins
Host Species

Escherichia coli (E. coli)
Applications

Elisa, WB
Tags:
Specification
Documents
Publications
Reviews
Product nameHuman Chromogranin A Partial [19-457] Recombinant Protein C- His Tag
Uniprot IDP10645
Uniprot linkhttp://www.uniprot.org/uniprot/P10645
Origin speciesHomo sapiens (Human)
Expression systemProkaryotic expression
SequenceMGLPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEWEDSKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLQALRRGLEHHHHHH
Molecular weight68.16KDa
Protein delivered with Tag?Yes
Purity estimated90%
BufferTris 50mMand 500mM Nacl pH7.5
FormLyophilized
Delivery conditionDry Ice
Delivery lead time in business days10-25
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Protein AccessionNP_001266.1
Spec:Entrez GeneID1113
Spec:NCBI Gene AliasesCGA
Spec:SwissProtIDP10645
Aliases /SynonymsChromograninA Partial [19-457], chromogranin A (parathyroid secretory protein 1), CHGA, Pituitary secretory protein I, SP-I,
ReferencePX-P2060
NoteFor research use only
Datasheet Download
MSDS Download

Publication

  • 1: Shanahan MA, Salem A, Fisher A, Cho CS, Leverson G, Winslow ER, Weber SM._x000D_ Chromogranin A predicts survival for resected pancreatic neuroendocrine tumors. J_x000D_ Surg Res. 2016 Mar;201(1):38-43. doi: 10.1016/j.jss.2015.10.006. Epub 2015 Oct_x000D_ 11. PubMed PMID: 26850182.
    • _x000D_ _x000D_ _x000D_
  • 2: Khan TM, Garg M, Warner RR, Uhr JH, Divino CM. Elevated Serum Pancreastatin Is_x000D_ an Indicator of Hepatic Metastasis in Patients With Small Bowel Neuroendocrine_x000D_ Tumors. Pancreas. 2016 Aug;45(7):1032-5. doi: 10.1097/MPA.0000000000000572._x000D_ PubMed PMID: 26684860.
    • _x000D_ _x000D_ _x000D_
  • 3: Mir SA, Zhang K, Milic M, Gu Y, Rieg T, Ziegler M, Vaingankar SM. Analysis and_x000D_ validation of traits associated with a single nucleotide polymorphism Gly364Ser_x000D_ in catestatin using humanized chromogranin A mouse models. J Hypertens. 2016_x000D_ Jan;34(1):68-78. doi: 10.1097/HJH.0000000000000760. PubMed PMID: 26556564.
    • _x000D_ _x000D_ _x000D_
  • 4: Kaiserova M, Prikrylova Vranova H, Galuszka J, Stejskal D, Mensikova K,_x000D_ Zapletalova J, Mares J, Kanovsky P. Orthostatic hypotension is associated with_x000D_ decreased cerebrospinal fluid levels of chromogranin A in early stage of_x000D_ Parkinson disease. Clin Auton Res. 2015 Oct;25(5):339-42. doi:_x000D_ 10.1007/s10286-015-0302-1. Epub 2015 Sep 10. PubMed PMID: 26359267.
    • _x000D_ _x000D_ _x000D_
  • 5: Choi Y, Miura M, Nakata Y, Sugasawa T, Nissato S, Otsuki T, Sugawara J,_x000D_ Iemitsu M, Kawakami Y, Shimano H, Iijima Y, Tanaka K, Kuno S, Allu PK, Mahapatra _x000D_ NR, Maeda S, Takekoshi K. A common genetic variant of the chromogranin A-derived _x000D_ peptide catestatin is associated with atherogenesis and hypertension in a_x000D_ Japanese population. Endocr J. 2015;62(9):797-804. doi:_x000D_ 10.1507/endocrj.EJ14-0471. Epub 2015 Jul 25. PubMed PMID: 26211667.
    • _x000D_ _x000D_ _x000D_
  • 6: Qi S, Huang M, Teng H, Lu Y, Jiang M, Wang L, Shi J, Ma Q, Gu G, Xin Y, Ma H. _x000D_ Autoantibodies to chromogranin A are potential diagnostic biomarkers for_x000D_ non-small cell lung cancer. Tumour Biol. 2015 Dec;36(12):9979-85. doi:_x000D_ 10.1007/s13277-015-3794-3. Epub 2015 Jul 18. PubMed PMID: 26186986.
    • _x000D_ _x000D_ _x000D_
  • 7: Yang X, Yang Y, Li Z, Cheng C, Yang T, Wang C, Liu L, Liu S. Diagnostic value _x000D_ of circulating chromogranin a for neuroendocrine tumors: a systematic review and _x000D_ meta-analysis. PLoS One. 2015 Apr 20;10(4):e0124884. doi:_x000D_ 10.1371/journal.pone.0124884. eCollection 2015. Review. PubMed PMID: 25894842;_x000D_ PubMed Central PMCID: PMC4403810.
    • _x000D_ _x000D_ _x000D_
  • 8: Zhu D, Xie H, Wang X, Liang Y, Yu H, Gao W. Correlation of plasma catestatin_x000D_ level and the prognosis of patients with acute myocardial infarction. PLoS One._x000D_ 2015 Apr 7;10(4):e0122993. doi: 10.1371/journal.pone.0122993. eCollection 2015._x000D_ PubMed PMID: 25848973; PubMed Central PMCID: PMC4388679.
    • _x000D_ _x000D_
  • 9: Wolf M, Riedlinger I, Lehmann R, Häring HU, Schleicher E, Peter A. Comparison _x000D_ of the automated KRYPTOR chromogranin A assay with the DAKO ELISA. Clin Lab._x000D_ 2014;60(12):2103-6. PubMed PMID: 25651748.
    • _x000D_ _x000D_ _x000D_
  • 10: Brehm Hoej L, Parkner T, Soendersoe Knudsen C, Grønbaek H. A comparison of_x000D_ three chromogranin A assays in patients with neuroendocrine tumours. J_x000D_ Gastrointestin Liver Dis. 2014 Dec;23(4):419-24. doi:_x000D_ 10.15403/jgld.2014.1121.234.3ca. PubMed PMID: 25532001.
    • _x000D_ _x000D_ _x000D_
  • 11: Wang YH, Yang QC, Lin Y, Xue L, Chen MH, Chen J. Chromogranin A as a marker_x000D_ for diagnosis, treatment, and survival in patients with gastroenteropancreatic_x000D_ neuroendocrine neoplasm. Medicine (Baltimore). 2014 Dec;93(27):e247. doi:_x000D_ 10.1097/MD.0000000000000247. PubMed PMID: 25501094; PubMed Central PMCID:_x000D_ PMC4602794.
    • _x000D_ _x000D_ _x000D_
  • 12: Chou WC, Chen JS, Hung YS, Hsu JT, Chen TC, Sun CF, Lu CH, Hwang TL. Plasma_x000D_ chromogranin A levels predict survival and tumor response in patients with_x000D_ advanced gastroenteropancreatic neuroendocrine tumors. Anticancer Res. 2014_x000D_ Oct;34(10):5661-9. PubMed PMID: 25275071.
    • _x000D_ _x000D_ _x000D_
  • 13: Hijioka M, Ito T, Igarashi H, Fujimori N, Lee L, Nakamura T, Jensen RT,_x000D_ Takayanagi R. Serum chromogranin A is a useful marker for Japanese patients with _x000D_ pancreatic neuroendocrine tumors. Cancer Sci. 2014 Nov;105(11):1464-71. doi:_x000D_ 10.1111/cas.12533. Epub 2014 Oct 18. PubMed PMID: 25220535; PubMed Central PMCID:_x000D_ PMC4462381.
    • _x000D_ _x000D_ _x000D_
  • 14: Mazzawi T, Gundersen D, Hausken T, El-Salhy M. Increased gastric chromogranin_x000D_ A cell density following changes to diets of patients with irritable bowel_x000D_ syndrome. Mol Med Rep. 2014 Nov;10(5):2322-6. doi: 10.3892/mmr.2014.2498. Epub_x000D_ 2014 Aug 18. PubMed PMID: 25174455; PubMed Central PMCID: PMC4214334.
    • _x000D_ _x000D_ _x000D_
  • 15: Qiao XW, Qiu L, Chen YJ, Meng CT, Sun Z, Bai CM, Zhao DC, Zhang TP, Zhao YP, _x000D_ Song YL, Wang YH, Chen J, Lu CM. Chromogranin A is a reliable serum diagnostic_x000D_ biomarker for pancreatic neuroendocrine tumors but not for insulinomas. BMC_x000D_ Endocr Disord. 2014 Aug 7;14:64. doi: 10.1186/1472-6823-14-64. PubMed PMID:_x000D_ 25099181; PubMed Central PMCID: PMC4130880.
    • _x000D_ _x000D_ _x000D_
  • 16: Dominguez N, Estevez-Herrera J, Borges R, Machado JD. The interaction between_x000D_ chromogranin A and catecholamines governs exocytosis. FASEB J. 2014_x000D_ Nov;28(11):4657-67. doi: 10.1096/fj.14-249607. Epub 2014 Jul 30. PubMed PMID:_x000D_ 25077558.
    • _x000D_ _x000D_ _x000D_
  • 17: Burgio SL, Conteduca V, Menna C, Carretta E, Rossi L, Bianchi E, Kopf B,_x000D_ Fabbri F, Amadori D, De Giorgi U. Chromogranin A predicts outcome in prostate_x000D_ cancer patients treated with abiraterone. Endocr Relat Cancer. 2014 May_x000D_ 8;21(3):487-93. doi: 10.1530/ERC-14-0071. Print 2014 Jun. PubMed PMID: 24741024.

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