Recombinant Human CYC1 Protein, N-His

Description of Recombinant Human CYC1 Protein, N-His

Introduction

Recombinant Human CYC1 Protein, also known as cytochrome c1, is a vital protein involved in cellular respiration and energy production. It is a component of the mitochondrial respiratory chain and plays a crucial role in the transfer of electrons during oxidative phosphorylation. This protein has been extensively studied and has a wide range of applications in both research and medical fields.

Structure of Recombinant Human CYC1 Protein

The CYC1 gene encodes for a protein of 261 amino acids with a molecular weight of approximately 30 kDa. The protein consists of three domains: a heme-binding domain, a membrane-binding domain, and a linker region. The heme-binding domain contains a single heme group, which is essential for the protein’s function. The membrane-binding domain anchors the protein to the inner mitochondrial membrane, while the linker region connects the two domains.

Activity of Recombinant Human CYC1 Protein

Recombinant Human CYC1 Protein is a key component of the mitochondrial respiratory chain, which is responsible for producing the majority of cellular energy in the form of adenosine triphosphate (ATP). This protein plays a crucial role in the transfer of electrons between complex III and complex IV of the respiratory chain. It accepts electrons from cytochrome c and transfers them to complex IV, which then uses the energy to pump protons across the inner mitochondrial membrane. This proton gradient is then used to generate ATP through the process of oxidative phosphorylation.

Aside from its role in energy production, Recombinant Human CYC1 Protein also has antioxidant properties. It can scavenge free radicals and protect cells from oxidative stress, which is a common cause of cellular damage and aging.

Applications of Recombinant Human CYC1 Protein

Recombinant Human CYC1 Protein has a wide range of applications in both research and medical fields. Some of its key applications include:

1. Study of Mitochondrial Function

As a crucial component of the mitochondrial respiratory chain, Recombinant Human CYC1 Protein is often used in studies to understand the function and regulation of mitochondria. It is also used to investigate the role of mitochondrial dysfunction in various diseases, such as neurodegenerative disorders and metabolic diseases.

2. Drug Discovery and Development

The function of Recombinant Human CYC1 Protein in cellular respiration and energy production makes it a potential target for drug development. Researchers are exploring the use of this protein in developing new drugs for the treatment of diseases associated with mitochondrial dysfunction, such as Parkinson’s disease and Alzheimer’s disease.

3. Diagnostic Tool

The levels of Recombinant Human CYC1 Protein in the blood have been linked to various diseases, including cancer and heart disease. As such, it can serve as a potential biomarker for disease diagnosis and monitoring.

4. Production of Antibodies

Recombinant Human CYC1 Protein can be used as an antigen to produce antibodies for research and diagnostic purposes. These antibodies can be used to detect the presence of the protein in various tissues and cells, aiding in the study of its function and localization.

5. Mitochondrial Replacement Therapy

Mitochondrial replacement therapy is a potential treatment for mitochondrial diseases caused by mutations in the mitochondrial DNA. Recombinant Human CYC1 Protein can be used in this therapy to replace the defective protein and restore normal mitochondrial function.

Conclusion

Recombinant Human CYC1 Protein is a crucial protein involved in cellular respiration and energy production. Its structure and function have been extensively studied, and it has a wide range of applications in both research and medical fields. This protein plays a vital role in maintaining cellular homeostasis and has the potential to be used in the development of new treatments for various diseases.