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Scientist running recombinant antibody expression in XtenCHO cell culture.

Recombinant antibody production services

From µg Screening to kg Production

Gene synthesis, expression, purification and quality control in one service. Choose high-throughput, transient or stable cell line production according to your project.

Get a 2-Minute Estimate Talk to a PhD Expert

  • Trusted by 9,000+ researchers worldwide
  • Powered by our proprietary XtenCHO™ Race expression platform
  • Starting at $296 per antibody
  • Clear, inclusive pricing

    From $296 per antibody

    Gene synthesis, codon optimization, expression, purification and QC included.

  • Production at every scale

    From µg to kg

    From multi-well plate screening to multi-liter production, with one partner throughout your project.

  • Ready to produce

    Every antibody format

    IgG, IgA, IgM, ScFv, Fab, VHH, ScFv-Fc, VHH-Fc, bispecifics, Fc-fusion. Your format, your backbone.

Get a Project Estimate
Use our price calculator

Complete our 2-minute project calculator to receive a personalized estimate for your recombinant antibody project.

Choose the right production method

Recombinant antibody production for every project stage

From parallel candidate screening to long-term antibody supply, choose the production service that matches your quantity, timeline and project goals.

    • Many candidates

    High-throughput antibody production

    Generate hundreds of antibodies for exploratory projects, lead optimization and AI-driven discovery.

    • Hundreds of antibodies in parallel
    • Milligram-scale production
    • Ideal for screening, optimization & AI training

    Explore high-throughput production →

    • Selected candidates

    Transient antibody production services

    Produce purified antibodies for characterization and functional studies in as little as 3 weeks..

    • Milligrams to several grams
    • Delivery in as little as 3 weeks
    • Powered by our XtenCHO™ Race platform

    Explore transient production →

    • Long-term supply

    Stable cell line development service

    Establish a reliable production cell line for long-term antibody supply.

    • Multigram-yield expression
    • Stable long-term production
    • 100% royalty-free

    Explore stable cell line development →

Find your ideal recombinant antibody production scale

  High-Throughput Transient Expression Stable Cell Line
Gene integration Transient — no genome integration Transient — no genome integration Permanent — stably integrated
Scale per antibody µg – mg
Multi-well plate
mg – grams
30 mL to multi-liter bioreactors
grams
Fed-batches
Throughput 100+ antibodies in parallel 1 to dozens antibodies Single clone per cell line
Turnaround From 15 days From 15 days From 4 months
Typical use Rapid variant screening
Lead candidate selection
AI model training datasets
Antibody optimization panels
Lead production & characterization
Antibody engineering validation
Preclinical in vitro studies
Preclinical studies
Regulatory submissions (IND/IVD)
Long-term consistent supply
Development stage Early discovery Lead optimization Preclinical
Royalties 100% royalty-free 100% royalty-free 100% royalty-free
Next stage Scale up to Transient Expression Scale up to transient expression in bioreactors
or Stable Cell line development
Transfer to partner CDMO for GMP manufacturing

Custom process

A recombinant antibody production workflow customized at every step

A simple, transparent workflow from project definition to purified antibody delivery.

  • 1

    Project definition

    Define your production requirements

    Format, quantity, timeline, application and quality requirements reviewed with your dedicated PhD expert.

  • 2.

    Production platform

    Choose your production method

    High-throughput expression, transient production or stable cell line development, according to your project stage and required scale.

  • 3.

    Gene synthesis & vector

    Customize your sequence and expression construct

    Codon optimization, gene synthesis and cloning into the selected expression vector.

  • 4.

    Production & purification

    Choose your purification level

    Default: Affinity chromatography using Protein A/G.

  • 5.

    Quality control

    Choose your QC level

    Default: Quantification by UV280, reducing and non-reducing SDS-PAGE, and purity evaluation.

    Proof of monoclonality by VIPS™ for stable cell lines.

  • 6.

    Delivery

    Receive your purified antibodies and complete project documentation

    Detailed report and purified antibody samples in PBS, pH 7.5, azide-free and sterilized by membrane filtration.

    Stable cell line included with the stable cell line development service.

high-productivity mammalian recombinant expression Xtencho

XtenCHO® Race
Up to 5× higher yield

than the market leader CHO SYstem

Our proprietary XtenCHO® Race platform is engineered for high-productivity mammalian transient expression. It produces more antibody from the same culture volume without feeding strategies or chemical boosters.

XtenCHO® Race has achieved up to 1.8 g/L in mammalian transient expression.

  • Up to 5×
    higher antibody yield in our comparative benchmark
  • 1.8 g/L
    highest yield achieved with XtenCHO® Race

Comparison of the production yield of 10 therapeutic antibodies with XtenCHO® Race vs Market Leader

Comparison of the production yield of 10 therapeutic antibodies with XtenCHO® Race vs Market Leader

XtenCHO® Race Case Reports

See our expertise through real antibody production projects

Explore how XtenCHO® Race performs across high-throughput candidate screening and mid-scale production for preclinical development.

High-throughput antibody production case study showing 7.24 mg per 30 mL yield, 18 antibodies expressed and 14-day production using XtenCHO® Race.

High-throughput expression service

Fast-tracking variant selection with XtenCHO® Race small-scale production

  • 7.24 mg / 30 mL
  • 14 days
  • 18 antibodies expressed

A mid-size Canadian biotech developing a therapeutic antibody for colorectal cancer needed to compare the production yields of 18 in-house antibody sequences. XtenCHO® Race small-scale expression enabled rapid yield comparison without using internal production resources.

Result: faster candidate selection with comparable production data across all 18 antibody variants.

Read the case report Explore High-Throughput Production

Mid-scale transient antibody production results with XtenCHO® Race showing 10.63 mg per 200 mL yield, low endotoxin and greater than 90 percent purity.

Transient expression service

Delivering preclinical-grade antibodies with XtenCHO® Race mid-scale production

  • 10.63 mg / 200 mL
  • <10 EU/mL endotoxin
  • >90% purity

A pharmaceutical company developing a recombinant antibody for rheumatoid arthritis needed to assess yield robustness during a 200 mL scale-up before advancing the lead candidate toward preclinical validation.

Result: preclinical-grade material meeting defined yield, endotoxin and purity requirements for the next development stage.

Read the case report Explore Transient Production

Want to see whether XtenCHO® Race fits your antibody project?

Discuss your sequence, scale and quality requirements with a PhD expert.

Discuss Your Project

Why ProteoGenix

Why choose us for custom recombinant antibody production?

  • Fully customizable

    Select the vector, expression strategy, purification, formulation and characterization required for your study.

  • Scalable solutions

    From µg to kg, we support your project from early discovery to industrial-scale production.

  • Extensive antibody formats

    IgG, IgA, IgM, IgE, Fab, scFv, VHH, bispecifics, Fc-fusion proteins. We can produce the format you require.

  • Competitive pricing

    One of the most cost-effective price on the market for antibody production, plus royalty-free stable cell line generation.

  • Engineer your antibodies faster than ever

    Thanks to the unique combination of our high-performance antibody production platform and AI-driven engineering solutions, you can optimize your antibodies faster than ever before!

  • Dedicated PhD support

    A scientific project manager helps define the production route and follows the project through delivery.

Trusted by 9,000+ Researchers Worldwide

  • Ramon Llull University

    Ramon Llull University, Spain

    Nathanaël Rakotoarinoro, PhD, Postdoctoral researcher

    “I have collaborated on several occasions with ProteoGenix for the production of recombinant antibodies. I greatly appreciated the responsiveness of the Account Manager, as well as their ability to identify the most appropriate solutions based on our needs and requirements. Overall, ProteoGenix’s services have often exceeded those of market leaders, and I have always been highly satisfied with the quality and quantity of the delivered products. This applies both to the antibodies produced and to the corresponding plasmids re-cloned into our in-house vectors, with a 100% success rate so far.”

  • LETI Pharma, Spain

    Jose Luis Donoso Muñoz, Project Manager

    “It was a real pleasure working with the Proteogenix team. Everything went very smoothly, the coordination was close and efficient, and they were always quick to respond to any doubts or questions. We truly appreciated how attentive they were throughout the entire process; at all times, we felt the communication was fluid and proactive. The delivery timelines were perfectly met, which made the collaboration even more seamless. I’d be happy to work together with them again in the future.”

  • University Hospital Basel, Switzerland

    Nicolas Kramer, PhD, Postdoctoral researcher

    “Working with ProteoGenix antibody production team has been an outstanding experience. The entire process was smooth, professional, and scientifically rigorous from start to finish. Communication was clear, timelines were met, and the final antibodies were delivered with a great amount of validation data. I truly appreciated ProteoGenix technical expertise and reliability, and I would gladly collaborate again in the future.”

Frequently asked questions

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