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View ProductsSize | 100ug, 1MG |
---|---|
Brand | ProteoGenix |
Isotype | IgG1, kappa |
Product type | Primary Antibodies |
Clonality | Monoclonal Antibody |
Expression system | XtenCHO |
Product name | Cafelkibart Biosimilar - Anti-CKR-L1 mAb - Research Grade |
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Source | CAS: 2851855-89-3 |
Origin species | Human |
Expression system | XtenCHO |
Purity | >95% by SDS-PAGE |
Buffer | 0.01M PBS, pH 7.4 |
Delivery condition | Blue ice (+4°C) |
Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
Storage condition | 4°C for short term; -20°C for long term |
Brand | ProteoGenix |
Aliases /Synonyms | anti-CKR-L1, CMKBR8, C-C CKR-8, GPR-CY6, CCR8, CMKBRL2, TER1, CCR-8, Chemokine receptor-like 1, CKRL1, CDw198, GPRCY6, C-C chemokine receptor type 8, CC-CKR-8, CC chemokine receptor CHEMR1 |
Reference | PX-TA2175-100 |
Note | For research use only. Not suitable for human use. |
Isotype | IgG1-kappa |
Clonality | Monoclonal Antibody |
Title: Introduction to Cafelkibart Biosimilar – Anti-CKR-L1 mAb
Cafelkibart Biosimilar – Anti-CKR-L1 mAb is a therapeutic antibody that has been developed as a biosimilar to the original anti-CKR-L1 monoclonal antibody (mAb). This biosimilar is designed to target the CKR-L1 protein, a cell surface receptor that has been implicated in various diseases. In this article, we will explore the structure, activity, and potential applications of this biosimilar in research.
Title: Structure of Cafelkibart Biosimilar – Anti-CKR-L1 mAb
Cafelkibart Biosimilar – Anti-CKR-L1 mAb is a recombinant humanized monoclonal antibody that is produced using advanced genetic engineering techniques. It consists of two heavy chains and two light chains, each containing variable and constant regions. The variable regions of the antibody are responsible for binding to the CKR-L1 protein, while the constant regions provide stability and effector functions. The antibody also contains a Fc region, which is important for its interaction with immune cells and other effector molecules.
Title: Activity of Cafelkibart Biosimilar – Anti-CKR-L1 mAb
The primary function of Cafelkibart Biosimilar – Anti-CKR-L1 mAb is to bind to the CKR-L1 protein and block its activity. This protein is known to play a role in various cellular processes, including cell proliferation, migration, and survival. By targeting CKR-L1, this biosimilar can inhibit these processes and potentially prevent or treat diseases associated with its overactivation. Additionally, the Fc region of the antibody can trigger immune responses, such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC), which can further enhance its therapeutic effects.
Title: Potential Applications of Cafelkibart Biosimilar – Anti-CKR-L1 mAb
Cafelkibart Biosimilar – Anti-CKR-L1 mAb has potential applications in various research areas, including oncology, immunology, and neurology. In oncology, this biosimilar can be used to target CKR-L1 in cancer cells and potentially inhibit their growth and spread. In immunology, it can be used to modulate immune responses and potentially treat autoimmune diseases. In neurology, this biosimilar can be used to target CKR-L1 in the brain and potentially treat neurodegenerative diseases.
Title: Advantages of Using Cafelkibart Biosimilar – Anti-CKR-L1 mAb
As a biosimilar, Cafelkibart Biosimilar – Anti-CKR-L1 mAb offers several advantages over the original anti-CKR-L1 mAb. Firstly, it is produced using advanced genetic engineering techniques, which ensure a high level of purity and consistency. Secondly, it is more cost-effective compared to the original mAb, making it more accessible to researchers. Additionally, being a biosimilar, it has been shown to have similar safety and efficacy profiles as the original mAb, making it a reliable alternative.
Title: Conclusion
In conclusion, Cafelkibart Biosimilar – Anti-CKR-L1 mAb is a therapeutic antibody that has been developed as a biosimilar to the original anti-CKR-L1 mAb. It has a well-defined structure and works by targeting the CKR-L1 protein and potentially inhibiting its activity. This biosimilar has potential applications in various research areas and offers several advantages over the original mAb. With its promising potential, Cafelkibart Biosimilar – Anti-CKR-L1 mAb is a valuable tool for researchers studying the role of CKR-L1 in various diseases.
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