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Human VEGF Recombinant Protein

Reference:
size

100ug, 50ug

Brand

ProteoGenix

Product type

Recombinant Proteins

Host Species

Escherichia coli (E. coli)

Applications

Elisa, WB

Product nameHuman VEGF Recombinant Protein
Uniprot IDP15692
Uniprot linkhttp://www.uniprot.org/uniprot/P15692
Origin speciesHomo sapiens (Human)
Expression systemProkaryotic expression
SequenceMAHNHRHKHKLDDDDKAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDR
Molecular weight14,65 kDa
Protein delivered with Tag?Yes
Purity estimated70%
BufferPBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol
FormFrozen
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Protein AccessionAAH65522.2
Spec:Entrez GeneID7422
Spec:NCBI Gene AliasesMVCD1, VPF, VEGF
Spec:SwissProtIDP15692
NCBI ReferenceAAH65522.2
Aliases /SynonymsVEGF, VEGFA protein, Vascular endothelial Growth Factor proteins A, VEGF-A, Vascular permeability factor, VPF, VEGFA
ReferencePX-P1060
NoteFor research use only.

SDS-PAGE for Human VEGF Recombinant Protein

Human VEGF Recombinant Protein, on SDS-PAGE under reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Publication

  • 1: Burmeister K, Quagliata L, Andreozzi M, Eppenberger-Castori S, Matter MS,_x000D_ Perrina V, Grobholz R, Jochum W, Horber D, Moosmann P, Lehmann F, Köberle D, Ng_x000D_ CK, Piscuoglio S, Tornillo L, Terracciano LM. Vascular endothelial Growth Factor proteins _x000D_ A amplification in colorectal cancer is associated with reduced M1 and M2_x000D_ macrophages and diminished PD-1-expressing lymphocytes. PLoS One. 2017 Apr_x000D_ 12;12(4):e0175563. doi: 10.1371/journal.pone.0175563. eCollection 2017. PubMed_x000D_ PMID: 28403223; PubMed Central PMCID: PMC5389821.
  • _x000D_ _x000D_ _x000D_
  • 2: Yin J, Shen L, Ji M, Wu Y, Cai S, Chen J, Yao Z, Ge J. Inverse Relationship_x000D_ between Serum VEGF Levels and Late In-Stent Restenosis of Drug-Eluting Stents._x000D_ Biomed Res Int. 2017;2017:8730271. doi: 10.1155/2017/8730271. Epub 2017 Mar 8._x000D_ PubMed PMID: 28373989; PubMed Central PMCID: PMC5360953.
  • _x000D_ _x000D_ _x000D_
  • 3: Ruffolo C, Toffolatti L, Canal F, Kotsafti A, Pagura G, Pozza A, Campo_x000D_ Dell'Orto M, Ferrara F, Massani M, Dei Tos AP, Castoro C, Bassi N, Scarpa M._x000D_ Colorectal polypoid lesions and expression of vascular endothelial Growth Factor proteins _x000D_ in a consecutive series of endoscopic and surgical patients. Tumour Biol. 2017_x000D_ Mar;39(3):1010428317692263. doi: 10.1177/1010428317692263. PubMed PMID: 28347226.
  • _x000D_ _x000D_ _x000D_
  • 4: Naykoo NA, Dil-Afroze, Rasool R, Shah S, Ahangar AG, Bhat IA, Qasim I, Siddiqi_x000D_ MA, Shah ZA. Single nucleotide polymorphisms, haplotype association and tumour_x000D_ expression of the vascular endothelial Growth Factor proteins (VEGF) gene with lung_x000D_ carcinoma. Gene. 2017 Apr 15;608:95-102. doi: 10.1016/j.gene.2017.01.007. Epub_x000D_ 2017 Jan 23. PubMed PMID: 28122267.
  • _x000D_ _x000D_ _x000D_
  • 5: Zhuo Y, Zeng Q, Zhang P, Li G, Xie Q, Cheng Y. VEGF Promoter Polymorphism_x000D_ Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese_x000D_ Population. Yonsei Med J. 2017 Mar;58(2):305-311. doi: 10.3349/ymj.2017.58.2.305._x000D_ PubMed PMID: 28120560; PubMed Central PMCID: PMC5290009.
  • _x000D_ _x000D_ _x000D_
  • 6: Dang YZ, Zhang Y, Li JP, Hu J, Li WW, Li P, Wei LC, Shi M. High VEGFR1/2_x000D_ expression levels are predictors of poor survival in patients with cervical_x000D_ cancer. Medicine (Baltimore). 2017 Jan;96(1):e5772. doi:_x000D_ 10.1097/MD.0000000000005772. PubMed PMID: 28072723; PubMed Central PMCID:_x000D_ PMC5228683.
  • _x000D_ _x000D_ _x000D_
  • 7: Martynova EV, Valiullina AH, Gusev OA, Davidyuk YN, Garanina EE, Shakirova VG,_x000D_ Khaertynova I, Anokhin VA, Rizvanov AA, Khaiboullina SF. High Triglycerides Are_x000D_ Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica. J_x000D_ Immunol Res. 2016;2016:8528270. doi: 10.1155/2016/8528270. Epub 2016 Dec 5._x000D_ PubMed PMID: 28053993; PubMed Central PMCID: PMC5178363.
  • _x000D_ _x000D_ _x000D_
  • 8: López-Cancio E, Ricciardi AC, Sobrino T, Cortés J, de la Ossa NP, Millán M,_x000D_ Hernández-Pérez M, Gomis M, Dorado L, Muñoz-Narbona L, Campos F, Arenillas JF,_x000D_ Dávalos A. Reported Prestroke Physical Activity Is Associated with Vascular_x000D_ Endothelial Growth Factor proteins Expression and Good Outcomes after Stroke. J Stroke_x000D_ Cerebrovasc Dis. 2017 Feb;26(2):425-430. doi:_x000D_ 10.1016/j.jstrokecerebrovasdis.2016.10.004. Epub 2016 Oct 28. PubMed PMID:_x000D_ 28029607.
  • _x000D_ _x000D_ _x000D_
  • 9: Ghazizadeh H, Fazilati M, Pasdar A, Avan A, Tayefi M, Ghasemi F, Mehramiz M,_x000D_ Mirhafez SR, Ferns GA, Azimi-Nezhad M, Ghayour-Mobarhan M. Association of a_x000D_ Vascular Endothelial Growth Factor proteins genetic variant with Serum VEGF level in_x000D_ subjects with Metabolic Syndrome. Gene. 2017 Jan 20;598:27-31. doi:_x000D_ 10.1016/j.gene.2016.10.034. Epub 2016 Oct 27. PubMed PMID: 27984191.
  • _x000D_ _x000D_ _x000D_
  • 10: Barchitta M, Maugeri A. Association between Vascular Endothelial Growth_x000D_ Factor Polymorphisms and Age-Related Macular Degeneration: An Updated_x000D_ Meta-Analysis. Dis Markers. 2016;2016:8486406. doi: 10.1155/2016/8486406. Epub_x000D_ 2016 Nov 23. PubMed PMID: 27999450; PubMed Central PMCID: PMC5141552.
  • _x000D_ _x000D_ _x000D_
  • 11: Li J, Sun K, Chen Z, Shi J, Zhou D, Xie G. A fluorescence biosensor for VEGF _x000D_ detection based on DNA assembly structure switching and isothermal amplification._x000D_ Biosens Bioelectron. 2017 Mar 15;89(Pt 2):964-969. doi:_x000D_ 10.1016/j.bios.2016.09.078. Epub 2016 Sep 30. PubMed PMID: 27816590.
  • _x000D_ _x000D_ _x000D_
  • 12: Rotar IC, Dumitras DE, Popp RA, Petrisor FM, Cotutiu P, Stamatian F, Muresan _x000D_ D. VEGF +936 C/T Genetic Polymorphism in Patients with Cervical Dysplasia. Anal_x000D_ Cell Pathol (Amst). 2016;2016:6074275. Epub 2016 Oct 12. PubMed PMID: 27812483;_x000D_ PubMed Central PMCID: PMC5080462.
  • _x000D_ _x000D_ _x000D_
  • 13: Hu ZQ, Xue H, Long JH, Wang Y, Jia Y, Qiu W, Zhou J, Wen ZY, Yao WJ, Zeng Z. _x000D_ Biophysical Properties and Motility of Human Mature Dendritic Cells Deteriorated _x000D_ by Vascular Endothelial Growth Factor proteins through Cytoskeleton Remodeling. Int J Mol _x000D_ Sci. 2016 Oct 31;17(11). pii: E1756. PubMed PMID: 27809226; PubMed Central PMCID:_x000D_ PMC5133777.
  • _x000D_ _x000D_ _x000D_
  • 14: Camerin GR, Brito AB, Vassallo J, Derchain SF, Lima CS. VEGF gene_x000D_ polymorphisms and outcome of epithelial ovarian cancer patients. Future Oncol._x000D_ 2017 Feb;13(5):409-414. doi: 10.2217/fon-2016-0299. Epub 2016 Oct 26. PubMed_x000D_ PMID: 27780361.
  • _x000D_ _x000D_ _x000D_
  • 15: Lee S, Kang HG, Choi JE, Lee JH, Kang HJ, Baek SA, Lee E, Seok Y, Lee WK, Lee_x000D_ SY, Yoo SS, Lee J, Cha SI, Kim CH, Cho S, Park JY. The Different Effect of VEGF_x000D_ Polymorphisms on the Prognosis of Non-Small Cell Lung Cancer according to Tumor_x000D_ Histology. J Korean Med Sci. 2016 Nov;31(11):1735-1741. doi:_x000D_ 10.3346/jkms.2016.31.11.1735. PubMed PMID: 27709850; PubMed Central PMCID:_x000D_ PMC5056204.

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