Obinutuzumab Biosimilar – Anti-MS4A1, CD20 mAb – Research Grade

Reference:
Size

,

Isotype

IgG1, kappa

Brand

Product type

Clonality

Expression system

Applications

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Product nameObinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade
SourceCAS 949142-50-1
SpeciesHumanized
Molecular weight150kDa
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsObinutuzumab,GA101,RG7159,RO5072759,afutuzumab,MS4A1, CD20,anti-MS4A1, CD20
ReferencePX-TA1172
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

General information on Anti-MS4A1/CD20(Homo sapiens) (Obinutuzumab) Monoclonal Antibody

Obinutuzumab is a humanized monoclonal antibody that can be used in combination with chlorambucil to treat chronic lymphocytic leukemia. It was sold under the Gazyva brand. There are black box warnings of fatal hepatitis B virus (HBV) reactivation and fatal progressive multifocal leukoencephalopathy (PML).

Publication

Joshua S. Bray, Gethin R. Thomas, Victoria M. Smith, Sandrine Jayne, Martin J.S. Dyer, Harriet S. Walter, Comparative in-Vitro Efficacy of CD20xCD3 IgG Bispecific Biosimilar Constructs Against Diffuse Large B Cell Lymphoma (DLBCL) Cell Lines with Different Levels of Expression of CD20, Blood, Volume 144, Supplement 1, 2024, Page 5826, ISSN 0006-4971, https://doi.org/10.1182/blood-2024-203884.

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