Can you combine functional, biophysical, and developability-related assays in a single study?

Yes, we offer customizable plans that integrate functional, biophysical, and developability assays to meet your specific needs, with the guidance of your dedicated PhD expert.

Is the service suitable for early discovery, lead selection, or preclinical development?

Yes, we have tailored solutions for early discovery, lead selection, and preclinical development to support your research at every stage.

What material and data are required to start a characterization study?

The materials required depend on the technique used but typically include a sequence and/or sample. We can adapt to all scenarios based on your project’s needs.

Can characterization data guide downstream optimization or development steps?

Yes, characterization data is essential for downstream optimization. We can use it to support our AI-driven developability services or a full wet-lab developability assessment to further refine your antibody.

How standardized and reproducible are your antibody characterization assays?

Our assays are highly standardized and designed for maximum reproducibility to ensure reliable, consistent results across different samples and batches, so you can trust your data for decision-making.

How do your services reduce the risk of late-stage failures?

By identifying potential issues early, such as binding affinity (KD determination), sequence integrity (through antibody sequencing), and developability risks (with our developability improvement service), we proactively address issues before they become costly failures at later stages.

Do you provide go/no-go recommendations based on characterization outcomes?

Yes, based on the characterization data, we provide go/no-go recommendations to help you make informed decisions about proceeding to the next development stage.

Can antibody characterization be integrated with discovery, optimization, and production services?

Yes, our characterization services can be seamlessly integrated with discovery, optimization, and production services like transient expression or stable cell line development to streamline your antibody development process.

Is the service compatible with different antibody formats (IgG, fragments, bispecifics)?

Yes, our characterization services are fully compatible with multiple antibody formats such as IgG, fragments, and bispecific antibodies, ensuring that we can support your project requirements.

Antibody Characterization Services

Get Clear Answers Faster with Our Complete Characterization portfolio

Techniques available

Week starting time

Properties studied

Design an Antibody Characterization Service That Fits Your Program

ProteoGenix offers a comprehensive toolbox of antibody characterization techniques, covering 12 key antibody characteristics in one place. Our experts work with you to select relevant properties to study and match them with the best analytical methods for your specific application. The result is a fully customized characterization plan, tailored to your molecule, timeline, and development goals.

Characterization your Antibody

Your Characterization Plan, Built Around Your Goals

Proven target engagement

Confirm binding strength: affinity (KD) → SPR (Biacore) / BLI
Understand interaction behavior: kon/koff kinetics → SPR / BLI
Validate in biological context: cell binding → SPRi

Dose & therapeutic window clarity

Support dose optimization: affinity + kinetics → SPR / BLI
Predict duration of action: dissociation profile → SPR / BLI
Define operating window: stability + aggregation risk → DSF/nanoDSF + DLS/SEC-HPLC

Minimize off-target risk

Improve selectivity confidence: specificity in complex samples → SPRi
Control behavior-shifting variants: PTM liabilities → In silico + MS
Reduce immunogenicity risks: PTM-driven red flags → MS mapping

Developability & formulation readiness

Avoid instability setbacks: thermal/conformational stability → DSF / nanoDSF
Prevent aggregation/precipitation: colloidal stability & size → DLS
Quantify aggregates: purity/aggregate species → SEC-HPLC (± SEC-MALS)

Identity & traceability locked

Confirm antibody identity: amino acid sequence → De novo MS
Secure traceability: DNA sequence record → DNA sequencing (sequenced + subcloned)
Detect mutations/variants: sequence checks → MS + DNA sequencing

Cleaner QC & safer preparations

Ensure low endotoxin: endotoxin level → LAL assay
Verify purity: aggregation state → SEC-HPLC + DLS
Support batch consistency: PTMs / glyco patterns → In silico + MS

Kick Start your Characterization Project

Reduce Regulatory Uncertainty with Expert-Guided Antibody Characterization services

Regulatory compliance & approval

Move faster toward approval with our regulatory-ready antibody characterization service. Your dedicated PhD project manager will guide you and provide the data you need.

Speak with our Characterization Experts