Recombinant Human CABYR Protein, N-GST & C-His

Reference: YHB36901
Product nameRecombinant Human CABYR Protein, N-GST & C-His
Origin speciesHuman
Expression systemProkaryotic expression
Molecular weight35.16 kDa
BufferLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
FormLiquid
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandAntibodySystem
Host speciesEscherichia coli (E.coli)
Fragment TypeGly13-Gly73
Aliases /SynonymsCalcium-binding protein 86, Testis-specific calcium-binding protein CBP86, FSP2, Calcium-binding tyrosine phosphorylation-regulated protein, CBP86, Cancer/testis antigen 88, CT88, CABYR, Fibrousheathin II, FSP-2, Fibrousheathin-2
ReferenceYHB36901
NoteFor research use only.

Description of Recombinant Human CABYR Protein, N-GST & C-His

Introduction

Recombinant Human CABYR Protein is a highly specialized protein that plays a crucial role in various cellular processes. This protein is produced through the process of recombinant DNA technology, where the gene encoding for CABYR is inserted into a host cell and then expressed to produce the desired protein. This recombinant protein has gained significant attention in the scientific community due to its unique structure, diverse activity, and potential applications in various fields.

Structure of Recombinant Human CABYR Protein

The recombinant human CABYR protein is composed of 186 amino acids and has a molecular weight of approximately 21 kDa. It contains two conserved domains, the CABYR-N and CABYR-C domains, which are essential for its function. The CABYR-N domain is responsible for binding to other proteins, while the CABYR-C domain is involved in protein-protein interactions.

The three-dimensional structure of the recombinant CABYR protein has been determined through X-ray crystallography, revealing a compact globular structure with a central beta-sheet surrounded by alpha-helices. This unique structure allows the protein to interact with different molecules and perform its diverse functions.

Activity of Recombinant Human CABYR Protein

The recombinant human CABYR protein has been shown to have multiple activities, including acting as an antigen, a binding partner, and a regulator of cellular processes.

Antigenic Activity

CABYR has been identified as an antigen in various types of cancer, including prostate, breast, and lung cancer. It is overexpressed in cancer cells and has been found to elicit an immune response in patients, making it a potential target for cancer immunotherapy.

Binding Activity

The CABYR protein has been shown to interact with a variety of proteins, including cytoskeletal proteins, kinases, and phosphatases. These interactions are essential for the proper functioning of the cell, such as cell division, motility, and signaling. CABYR has also been found to bind to sperm-specific proteins, suggesting a role in sperm function and fertility.

Regulatory Activity

Studies have shown that CABYR can regulate the activity of certain enzymes, such as protein kinase A and phosphatase 2A, by binding to them and altering their activity. This regulatory activity is crucial for maintaining the balance of cellular processes and has implications in various diseases, including cancer and infertility.

Applications of Recombinant Human CABYR Protein

The unique structure and diverse activities of the recombinant human CABYR protein make it a promising candidate for various applications in the fields of cancer research, reproductive medicine, and drug development.

Cancer Research

As an antigen in cancer cells, CABYR can be used as a diagnostic marker for cancer detection and monitoring. It can also be targeted for cancer immunotherapy, where the immune system is stimulated to recognize and destroy cancer cells expressing CABYR.

Reproductive Medicine

Due to its presence in sperm cells, CABYR has been investigated as a potential biomarker for male fertility. It can also be used in assisted reproductive techniques, such as in vitro fertilization, to improve the success rate of fertilization.

Drug Development

The regulatory activity of CABYR makes it a potential target for drug development. By modulating the activity of enzymes involved in various diseases, such as cancer and infertility, CABYR can be targeted for the development of novel therapeutics.

Conclusion

In conclusion, Recombinant Human CABYR Protein is a unique and versatile protein with a compact globular structure and diverse activities. Its potential applications in cancer research, reproductive medicine, and drug development make it

Reviews

There are no reviews yet.

REVIEW YOUR PRODUCT

Be the first to review “Recombinant Human CABYR Protein, N-GST & C-His”

Your email address will not be published. Required fields are marked *

Contact us

Send us a message from the form below







    Cart (0 Items)

    Your cart is currently empty.

    View Products