Recombinant Human MYL6B, N-His

Description of Recombinant Human MYL6B, N-His

Introduction

Recombinant Human MYL6B, N-His is a protein that has been genetically engineered to mimic the structure and function of a naturally occurring protein called Myosin Light Chain 6B (MYL6B). This protein plays a crucial role in muscle contraction and is a potential drug target for various muscle-related disorders. In this article, we will explore the structure, activity, and potential applications of Recombinant Human MYL6B, N-His.

Structure of Recombinant Human MYL6B, N-His

Recombinant Human MYL6B, N-His is a 19.7 kDa protein that consists of 167 amino acids. It is composed of two domains, the N-terminal domain and the C-terminal domain, which are connected by a flexible linker. The N-terminal domain is responsible for binding to the actin filaments, while the C-terminal domain binds to the regulatory light chain of the myosin head. This structure is similar to the naturally occurring MYL6B protein, making it an effective substitute for therapeutic purposes.

Activity of this protein

The primary function of MYL6B is to regulate muscle contraction by binding to the actin filaments and facilitating the movement of the myosin head. Recombinant Human MYL6B, N-His mimics this activity and can effectively regulate muscle contraction in vitro. It has been shown to have a high affinity for the actin filaments and can effectively displace the native MYL6B protein, making it a potential therapeutic agent for muscle-related disorders.

Potential Applications

Recombinant Human MYL6B, N-His has shown promising results in various pre-clinical studies and has the potential to be used in the treatment of various muscle-related disorders. One of the potential applications of this protein is in the treatment of muscle spasms and cramps. By regulating muscle contraction, Recombinant Human MYL6B, N-His can effectively reduce the severity and frequency of muscle spasms and cramps.

Another potential application of Recombinant Human MYL6B, N-His is in the treatment of muscular dystrophy. Muscular dystrophy is a genetic disorder that causes progressive muscle weakness and degeneration. Recombinant Human MYL6B, N-His can potentially improve muscle function and strength in individuals with muscular dystrophy by regulating muscle contraction.

Furthermore, Recombinant Human MYL6B, N-His has also shown potential in the treatment of heart diseases. The heart muscle is responsible for pumping blood throughout the body, and any dysfunction in its contraction can lead to serious heart conditions. By regulating the contraction of the heart muscle, Recombinant Human MYL6B, N-His can potentially improve heart function and prevent heart diseases.

Conclusion

In conclusion, Recombinant Human MYL6B, N-His is a genetically engineered protein that mimics the structure and function of the naturally occurring MYL6B protein. It has a similar structure and activity, making it an effective substitute for therapeutic purposes. This protein has shown potential in the treatment of various muscle-related disorders, including muscle spasms, muscular dystrophy, and heart diseases. Further research and clinical trials are needed to fully explore the potential of Recombinant Human MYL6B, N-His as a drug target for these conditions.