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📢 -40% on Recombinant Antibody Production. Available until January 31, 2026 on your first order. Code: RECAB40

Antibody Drug Conjugate (ADC) Services

High control ADCs for real-world therapeutic development

 

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Conjugation technologies
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From antibody to ADC
>0%
DAR homogeneity

Two conjugation technologies to power every ADC challenge, from proof of concept to clinical-ready material

ProteoGenix offers an extensive portfolio of chemical and enzymatic conjugation solutions. We help you select the optimal strategy based on key criteria such as:

  • Antibody structure
  • Payload properties
  • Scale-up requirements
  • Regulatory constraints

Whether you’re validating a concept or preparing for clinical phases, our experts and versatile conjugation toolbox ensure the most suitable solution for your program.

ADC properties

Convert any antibody format into a potent ADC

Our platform supports all antibody formats, from VHHs to IgGs, including Fabs, scFvs, and bispecific antibodies.

Conjugate your antibody

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Achieve controlled toxicity profiles

Perfectly controlled Drug-to-Antibody Ratio (DAR)

Our chemical and enzymatic conjugation technologies are designed to deliver >90% DAR homogeneity at the ratio you specify.
This tight DAR control, and its distribution, is essential for reducing ADC toxicity and avoiding the site-barrier effect.

Broad selection of linkers and payloads

Choose from a wide panel of cleavable and non-cleavable linkers, with expert guidance to ensure:

  • High stability in circulation to prevent premature payload release
  • Fast and targeted payload release inside the tumor cells

We also offer an extensive selection of payloads to tailor the optimal DAR/linker/payload configuration for your therapeutic objective.

Get a complete ADC characterization package

We provide a full analytical suite, including: DAR, DAR distribution, drug location, % free drug, and all standard antibody QC measurements.

More reasons to choose ProteoGenix for your ADC development

  • From antibody generation to conjugation, we support every step. This integrated approach lets us also fine-tune antibody affinity and kinetics, two critical factors that directly impact your ADC’s therapeutic success.

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ProteoGenix’s ADC development workflow – From your antibody to your ADC in 3 weeks

From your antibody to your ADC in 3 weeks (does not include the optional steps)

Antibody selection (optional)
  • Customer provides the antibody

or

Antibody optimization (optional)
Antibody conjugation
  • Selection of the optimal antibody/linker/payload combination
  • Chemical or enzymatic conjugation
ADC characterization
  • DAR
  • DAR distribution
  • Additional QC analyses

FAQ about our ADC development service

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