Recombinant Human IFNA1/Interferon alpha-D Protein, GST

Description of Recombinant Human IFNA1/Interferon alpha-D Protein, GST

Introduction

Recombinant Human IFNA1, also known as Interferon alpha-D, is a type I interferon protein that plays a crucial role in the body’s immune response against viral infections and cancer. This protein is produced through recombinant DNA technology, where the gene for IFNA1 is inserted into a host cell, allowing for large-scale production of the protein. In this article, we will discuss the structure, activity, and applications of Recombinant Human IFNA1.

Structure of Recombinant Human IFNA1

Recombinant Human IFNA1 is a glycoprotein, meaning it contains both carbohydrates and proteins. It is composed of 165 amino acids and has a molecular weight of approximately 19 kDa. The protein has a three-dimensional structure, with a long alpha-helical domain and a short beta-sheet domain. This structure is essential for the protein’s function as it allows for specific interactions with its target receptors.

Activity of Recombinant Human IFNA1

Recombinant Human IFNA1 is a potent cytokine that plays a crucial role in the body’s immune response. It acts as an antiviral agent by stimulating the production of enzymes that inhibit viral replication. Additionally, IFNA1 can activate immune cells such as natural killer cells and macrophages, which are responsible for killing infected cells. This protein also has anti-tumor activity, as it can inhibit the growth and proliferation of cancer cells.

Applications of Recombinant Human IFNA1

Recombinant Human IFNA1 has various applications in both research and medicine. One of the primary uses of this protein is in the treatment of viral infections, such as hepatitis B and C, human papillomavirus, and herpes simplex virus. It is also used in the treatment of certain types of cancer, including leukemia, melanoma, and renal cell carcinoma.

In research, Recombinant Human IFNA1 is used to study the immune response to viral infections and cancer. It is also used to investigate the role of IFNA1 in autoimmune diseases, such as lupus and multiple sclerosis. This protein is also a valuable tool in vaccine development, as it can be used to enhance the body’s immune response to a specific antigen.

Recombinant Human IFNA1 as an Antigen

In addition to its therapeutic and research applications, Recombinant Human IFNA1 is also used as an antigen in diagnostic tests. This protein can be used to detect the presence of antibodies against IFNA1 in the blood, which can indicate an ongoing viral infection or autoimmune disease.

Conclusion

In summary, Recombinant Human IFNA1 is a vital protein in the body’s immune response against viral infections and cancer. Its structure and activity allow it to act as an antiviral and anti-tumor agent, making it a valuable tool in medicine and research. With its various applications and use as an antigen, Recombinant Human IFNA1 continues to play a crucial role in advancing our understanding and treatment of diseases.