XtenCHO ™ Race Cells

Description of XtenCHO ™ Race Cells

XtenCHO Race: High-Yield Transient Gene Expression in Just 8 Days

XtenCHO Race cells are a next-generation Chinese Hamster Ovary (CHO) cell line, derived from CHO-K1, specifically optimized for rapid and high-yield transient gene expression. Engineered to deliver exceptional protein production, these cells allow researchers to achieve high titers in just 8 days of culture, making them an ideal choice for accelerating biopharmaceutical development.
Why Use CHO Cells for Transient Expression?

CHO cells have become the preferred expression system in therapeutic research due to their unique advantages:

-Human-Like Protein Quality: CHO cells ensure correct protein folding, post-translational modifications, and glycosylation patterns, crucial for functional biologics.
-High Transfection Efficiency: CHO cells readily uptake and express exogenous DNA, allowing for robust protein production.
-Scalability & Adaptability: From small-scale research to large-scale bioreactor production, CHO cells are well-suited for flexible bioprocessing needs.
-Proven Regulatory Acceptance: CHO-derived proteins are widely used in drug development, easing the transition from research to clinical applications.

Why Choose XtenCHO Race?

XtenCHO Race cells set a new benchmark for speed and efficiency in transient gene expression:

-Ultra-Fast Production: High-yield protein expression in just 8 days, significantly cutting production timelines.
-Optimized for Maximum Output: Engineered to surpass standard CHO-K1 cells in transient transfection efficiency and protein yield.
-Seamless Implementation: Compatible with commonly used transfection reagents and culture conditions, ensuring an easy transition into existing workflows.

With XtenCHO Race, researchers can accelerate therapeutic development, improve reproducibility, and optimize protein expression strategies, making it the ideal choice for fast and scalable transient gene expression.

XtenCHO™ Race outperforms up to 6X (Cixutumumab and Peresolimab)

Crude production yields in mg/L obtained in 24-well plates cultures without feeding (Octet Analysis) Yields in flask (better aeration) will be 1.5 to 2.5 Higher for Human/humanized IgG1/IgG4 (depending on the antibody considered)