New Service : Single B Cell Screening ! 30% off on your quote request, from March 20th to April 16th,2023 with the code SPRING23 !
Need to develop a monoclonal antibody with maximized developability?
We guarantee at least 3 binders to your antigen of interest
We make sure you get antibodies with best physicochemical characteristics to get maximum developability
Our screening method allows to perform different screening in a highly efficient manner
We guarantee a VL and VH natural pairing
Our screening method generates a high repertoire of antibodies thus preserving B cell natural diversity
If you get 3 binders, pay 100% If no binders, we charge minimal fees only
Benefit from our system optimized for high yields and high-throughput antibody production
Get your antibody sequence within 2 months for the whole process including animal immunization
Be the owner of the antibody sequences that we generate for you
Additional services
ELISA for positive/negative screening (Against one specific peptide/protein/small molecule- cross reactivity profiling)
Competitive ELISA (To identify clones with blocking/ neutralizing activity)
Single B-cell sequencing is an efficient monoclonal antibody development and screening strategy which principle is based on the amplification of genes encoding the VH and VL region from B-cells directly. This technology presents several advantages making it a very useful approach for antibody biology understanding and for antibody use in clinical essays. Among these advantages, single B-cell sorting is characterized by:
To date, several techniques have been developed to isolate and screen monoclonal antibodies (mAbs). This table summarizes the main advantages and drawbacks of each technique.